Almotriptan Malate

Basic Information

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CAS Number

181183-52-8

Molecular Formula

C21H31N3O7S

Molecular Weight

469.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

171-175°C

Boiling Point

538.7ºC at 760mmHg

Density

1.27g/cm3

Flash Point

279.6ºC

SMILES

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CN(C)CCC1=CNC2=C1C=C(C=C2)CS(=O)(=O)N3CCCC3.C(C(C(=O)O)O)C(=O)O

InChI

InChI=1S/C17H25N3O2S.C4H6O5/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23(21,22)20-8-3-4-9-20;5-2(4(8)9)1-3(6)7/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3;2,5H,1H2,(H,6,7)(H,8,9)

InChIKey

QHATUKWEVNMHRY-UHFFFAOYSA-N

LogP

1.1042

Topological Polar Surface Area

151.23999999999998 Å²

Hydrogen Bond Donor/Acceptor

4 / 10

Complexity

612

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Almotriptan d,l-hydrogenmalate
CHEMBL1200521
BCP9000276
ALMOTRIPTAN MALATE (MART.)
Almotriptan malate (USP)
HMS3651A12
1-(((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)sulfonyl)pyrrolidine, hydroxybutanedioate (1:1)
D02825
1-[({3-[2-(Dimethylamino)ethyl]indol-5-yl}methyl)sulfonyl]pyrrolidine malate (1:1)
J-011571
BCP05632
Almotriptan (malate)
Almotriptan Malate(PNU180638)
3-[2-(Dimethylamino)ethyl]-5-(pyrrolidin-1-ylsulfonylmethyl )-1H-indole malate
N,N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine;2-hydroxybutanedioic acid
SMR004701216
1-(((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)sulfonyl)pyrrolidine hydroxybutanedioate
ALMOTRIPTAN MALATE [VANDF]
SR-05000001986-2
MLS006010048
SW219418-1
AS-12142
DTXSID1044225
SR-05000001986
FT-0661519
ALMOTRIPTAN MALATE (EP MONOGRAPH)
PNU180638
ALMOTRIPTAN MALATE [WHO-DD]
Almotriptan maleate
LAS-31416-D,L-MALATE-ACID
1-(((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)sulfonyl)pyrrolidine, hydroxybutanedionate (1:1)

MDL Number

MFCD08067740

FAQ

What is Almotriptan Malate (CAS: 181183-52-8)?

Almotriptan Malate is a triptan medication used to treat migraine headaches. It is a white to off-white crystalline powder with a molecular formula of C19H23N3O4·C4H6O4 and a molecular weight of 441.46. It is known for its analgesic and anti-inflammatory properties.

What are the main uses of Almotriptan Malate (CAS: 181183-52-8)?

Almotriptan Malate is primarily used to treat acute migraine attacks in adults. It is available in tablet form and is effective in reducing the severity of migraine symptoms such as headache pain, nausea, and sensitivity to light and sound.

Is Almotriptan Malate (CAS: 181183-52-8) safe?

Almotriptan Malate is generally considered safe when used as directed. However, it should be used with caution in patients with cardiovascular disease, hypertension, or history of stroke. Common side effects include dizziness, nausea, and fatigue. Always consult a healthcare provider before use.

How should Almotriptan Malate (CAS: 181183-52-8) be stored?

Almotriptan Malate should be stored at a temperature between 15°C and 30°C (59°F and 86°F) and protected from moisture and light. Store the tablets in a tight, light-resistant container and keep out of reach of children. Do not expose to extreme temperatures or store in the bathroom.