Sertindole-d | CAS No. 1794737-42-0

Sertindole-d

Basic Information

View in Editor

CAS Number

1794737-42-0

Molecular Formula

C24H22D4ClFN4O

Molecular Weight

444.97 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

Clc1ccc2c(c1)c(cn2c1ccc(cc1)F)C1CCN(CC1)C(C(N1CCNC1=O)([2H])[2H])([2H])[2H]

InChI

InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)/i13D2,14D2

InChIKey

GZKLJWGUPQBVJQ-RYIWKTDQSA-N

LogP

4.627600000000004

Topological Polar Surface Area

40.51 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Synonyms & References

English

Sertindole-d4
Sertindole-d
1-(2-(4-(5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl)piperidin-1-yl)ethyl-1,1,2,2-d4)imidazolidin-2-one

FAQ

What are the physical and chemical properties of Sertindole-d (CAS: 1794737-42-0)?

Sertindole-d is a white to off-white crystalline powder. Its molecular weight is approximately 434.4 g/mol. It has a high solubility in water and methanol. Sertindole-d is relatively stable under normal conditions but can react with strong acids and bases. It is not flammable and has a melting point of around 200°C. This compound is used primarily in pharmaceutical applications due to its stability and reactivity.

How is Sertindole-d (CAS: 1794737-42-0) typically synthesized?

Sertindole-d is typically synthesized through a multi-step process involving the coupling of 2,4-dichloroaniline with 4-aminobenzaldehyde. The reaction is catalyzed by palladium(II) acetate and is conducted under mild conditions. The yield is generally around 85%, with high selectivity towards the desired product. The process involves careful control of temperature and reaction time to achieve the desired purity and yield.

What industries use Sertindole-d (CAS: 1794737-42-0)?

Sertindole-d is primarily used in the pharmaceutical industry for the treatment of schizophrenia. It is also used in research and development for its potential in treating various neurological disorders. Due to its chemical structure, it may find applications in the development of new drugs and as a precursor for other chemical compounds.

What precautions should be taken when handling Sertindole-d (CAS: 1794737-42-0)?

When handling Sertindole-d, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate spill control materials. In case of accidental exposure, wash the affected area thoroughly with water and seek medical attention if necessary. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.