Gemifioxacin | CAS No. 175463-14-6

Gemifioxacin

Basic Information

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CAS Number

175463-14-6

Molecular Formula

C18H20FN5O4

Molecular Weight

389.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

235-237°

SMILES

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CON=C1CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F

InChI

InChI=1S/C18H20FN5O4/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27)/b22-14+

InChIKey

ZRCVYEYHRGVLOC-HYARGMPZSA-N

LogP

2.3

Topological Polar Surface Area

123.04 Å²

Hydrogen Bond Donor/Acceptor

3 / 9

Complexity

725

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Gemifloxacin (INN)
HY-116229
SB 265805
204519-64-2
J01MA15
SB-265805
7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
7-{3-Aminomethyl-4-[(Z)-methoxyimino]-pyrrolidin-1-yl}-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid
CHEBI:101853
Gemifloxacin [INN]
SBI-0206906.P001
HSDB 8027
SB-265805S;LB-20304a
BSPBio_002308
Gemifloxacin
7-(3-Aminomethyl-4-methoxyimino-pyrrolidine-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-(1,8)-naphthyridine-3-carboxylic acid
7-[3-(aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
CHEMBL430
7-[(4Z)-3-(aminomethyl)-4-methoxyimino-pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Gemifloxacinum
GEMIFLOXACIN [MI]
SCHEMBL13414391
DB01155
Gemifloxacine
LB 20304
Gemifioxacin
1,8-Naphthyridine-3-carboxylic acid, 7-((4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-
7-(3-(aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
BDBM50178917
(S,Z)-7-(3-(aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
SR-05000001958

MDL Number

MFCD07779399

Customs Code

2933990090

FAQ

What regulatory guidelines apply to Gemifloxacin (CAS: 175463-14-6)?

Gemifloxacin (CAS: 175463-14-6) falls under the classification of antibiotics. Regulatory guidelines include OSHA and EPA standards for handling, the FDA for pharmaceutical use, and REACH for chemical safety. Proper labeling and storage are required, with disposal following environmental protection regulations.

Are there alternatives to Gemifloxacin (CAS: 175463-14-6) in synthesis?

While Gemifloxacin (CAS: 175463-14-6) is a potent antibiotic, alternatives include other fluoroquinolones like Ciprofloxacin and Levofloxacin. Synthesis can also utilize derivatives such as moxifloxacin or newer generation fluoroquinolones, which may offer improved efficacy or reduced side effects.

What is the market or research trend for Gemifloxacin (CAS: 175463-14-6)?

Market trends for Gemifloxacin (CAS: 175463-14-6) suggest a declining use due to resistance issues. However, ongoing research focuses on optimizing its pharmacokinetics and developing combination therapies. Emerging trends include the exploration of new fluoroquinolones targeting resistant strains.

How should waste containing Gemifloxacin (CAS: 175463-14-6) be handled?

Waste containing Gemifloxacin (CAS: 175463-14-6) should be collected in sealed containers, labeled appropriately, and disposed of through professional waste disposal services. Incineration is a common method, but environmental protection measures must be followed to minimize ecological impact. Proper training and adherence to local regulations are essential.