4-Chloro-3-methoxypyridine-2-carboxylic acid

Basic Information

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CAS Number

170621-86-0

Molecular Formula

C7H6ClNO3

Molecular Weight

187.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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COC1=C(C=CN=C1C(=O)O)Cl

InChI

InChI=1S/C7H6ClNO3/c1-12-6-4(8)2-3-9-5(6)7(10)11/h2-3H,1H3,(H,10,11)

InChIKey

HRIXILRILGXVGH-UHFFFAOYSA-N

LogP

1.4417999999999997

Topological Polar Surface Area

59.42 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

176

Synonyms & References

English

4-Chloro-3-methoxypicolinic acid
4-CHLORO-3-METHOXYPYRIDINE-2-CARBOXYLIC ACID
4-CHLORO-3-METHOXYPYRIDINE-2-CARBOXYLIC ACID?
4-Chloro-3-Methoxy-2-Pyridinecarboxylic Acid
4-chloro-3-methoxy-pyridine-2-carboxylic acid
4-chloro-3-methoxypyridine-2-carboxylic acid
4-chloro-3-methoxypicolinic acid
AS-66284
HRIXILRILGXVGH-UHFFFAOYSA-N
4-chloro-3-methoxypicolinicacid
170621-86-0
SCHEMBL1101605
CS-0102804
SY153590
PB41213
A15295
EN300-135352
MFCD09909844
AKOS006312133
F11124
VGA62186
DTXSID90628934
AM84596

MDL Number

MFCD09909844

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Chloro-3-methoxypyridine-2-carboxylic acid (CAS: 170621-86-0)?

4-Chloro-3-methoxypyridine-2-carboxylic acid (CAS: 170621-86-0) crystallizes as a white powder. The molecular weight is approximately 227.01 g/mol. It is slightly soluble in water but has higher solubility in organic solvents like ethanol and acetonitrile. It is moderately reactive towards bases and nucleophiles. It can form complexes with metal ions and exhibits spectroscopic properties useful in analytical chemistry.

How is 4-Chloro-3-methoxypyridine-2-carboxylic acid (CAS: 170621-86-0) typically synthesized?

4-Chloro-3-methoxypyridine-2-carboxylic acid (CAS: 170621-86-0) is typically synthesized via the condensation reaction of 2-chloro-3-methoxypyridine with acetic anhydride in the presence of a catalyst like pyridine. The reaction is carried out under mild heating and results in a high yield of 85-90%.

What industries use 4-Chloro-3-methoxypyridine-2-carboxylic acid (CAS: 170621-86-0)?

4-Chloro-3-methoxypyridine-2-carboxylic acid (CAS: 170621-86-0) finds applications in the pharmaceutical industry for the synthesis of certain drugs, as a reagent in analytical chemistry, and as a precursor in the production of other organic compounds. It is also used in the development of sensors and in materials science for the synthesis of novel polymers.

What precautions should be taken when handling 4-Chloro-3-methoxypyridine-2-carboxylic acid (CAS: 170621-86-0)?

When handling 4-Chloro-3-methoxypyridine-2-carboxylic acid (CAS: 170621-86-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Store in a fume hood to prevent inhalation risk. Avoid skin contact and ingestion. In case of spill, neutralize with a base and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.