1-{4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl}-2-propen-1-one | CAS No. 1698055-85-4

1-{4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl}-2-propen-1-one

Basic Information

CAS Number

1698055-85-4

Molecular Formula

C21H17ClF2N4O2

Molecular Weight

430.84 g/mol

AD

Basic Physical Properties

C=CC(=O)N1CCN(CC1)c2c3cc(c(c(c3ncn2)F)c4c(cccc4F)O)Cl

InChI

InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25-11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2

InChIKey

ZRPZPNYZFSJUPA-UHFFFAOYSA-N

LogP

3.7686000000000033

Topological Polar Surface Area

69.56 Ų

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

636

Synonyms & References

English

  • ARS-1620
  • ARS1620
  • (S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
  • 1-(4-(6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
  • 1-[4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl]piperazin-1-yl]prop-2-en-1-one
  • GTPL10383
  • AMY16838
  • ARS

MDL Number

MFCD31619312

FAQ

What regulatory guidelines apply to 1-{4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl}-2-propen-1-one (CAS: 1698055-85-4)?

1-{4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl}-2-propen-1-one (CAS: 1698055-85-4) falls under the scope of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations in the European Union, and FDA/EPA guidelines for pharmaceutical and chemical substances. Ensure proper labeling, storage, and handling to comply with these regulations.

Are there alternatives to 1-{4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl}-2-propen-1-one (CAS: 1698055-85-4) in synthesis?

Alternative reagents such as 1-{4-[6-bromo-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl}-2-propen-1-one or other quinazoline derivatives can be used as alternatives in the synthesis process. These alternatives can offer similar or different functionalities based on the specific application requirements.

What is the market or research trend for 1-{4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl}-2-propen-1-one (CAS: 1698055-85-4)?

The market for 1-{4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl}-2-propen-1-one (CAS: 1698055-85-4) is growing due to its potential in pharmaceutical applications. Research trends focus on its biological activity and its use in drug discovery. However, market dynamics are influenced by regulatory approvals and pricing.

How should waste containing 1-{4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl}-2-propen-1-one (CAS: 1698055-85-4) be handled?

Waste containing 1-{4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl}-2-propen-1-one (CAS: 1698055-85-4) should be collected in a leak-proof container and stored in a secure location. For safe disposal, consult a professional hazardous waste management service. Ensure all disposal methods comply with local environmental and safety regulations to prevent contamination and protect the environment.

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