AC-Ile-tyr-gly-glu-phe-NH2

Basic Information

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CAS Number

168781-78-0

Molecular Formula

C33H44N6O9

Molecular Weight

668.75 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CCC(C)C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CC2=CC=CC=C2)C(=O)N)NC(=O)C

InChI

InChI=1S/C33H44N6O9/c1-4-19(2)29(36-20(3)40)33(48)39-26(17-22-10-12-23(41)13-11-22)31(46)35-18-27(42)37-24(14-15-28(43)44)32(47)38-25(30(34)45)16-21-8-6-5-7-9-21/h5-13,19,24-26,29,41H,4,14-18H2,1-3H3,(H2,34,45)(H,35,46)(H,36,40)(H,37,42)(H,38,47)(H,39,48)(H,43,44)/t19-,24-,25-,26-,29-/m0/s1

InChIKey

OZPPBQMEFADOEU-QAXPSLGGSA-N

LogP

-0.351099999999992

Topological Polar Surface Area

246.11999999999998 Å²

Hydrogen Bond Donor/Acceptor

9 / 15

Complexity

1120

Synonyms & References

English

AC-ILE-TYR-GLY-GLU-PHE-NH2
Ac-Ile-Tyr-Gly-Glu-Phe-NH?
P60c-src Substrate II
AC-IYGEF-NH2
SRC SUBSTRATE II
M 2165
HY-P3773
(4S)-4-[[2-[[(2S)-2-[[(2S,3S)-2-acetamido-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-5-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
MFCD00798781
CS-0620671
168781-78-0
CHEMBL336741

MDL Number

MFCD00798781

FAQ

What are the physical and chemical properties of AC-Ile-tyr-gly-glu-phe-NH2 (CAS: 168781-78-0)?

AC-Ile-tyr-gly-glu-phe-NH2 (CAS: 168781-78-0) is a crystalline peptide with a molecular weight of approximately 719.44 g/mol. It has a very low solubility in water and is moderately soluble in organic solvents. The peptide is relatively stable but can react with strong acids or bases. Its reactivity is moderate and depends on the presence of specific functional groups.

How is AC-Ile-tyr-gly-glu-phe-NH2 (CAS: 168781-78-0) typically synthesized?

AC-Ile-tyr-gly-glu-phe-NH2 (CAS: 168781-78-0) is typically synthesized via solid-phase peptide synthesis (SPPS). The reaction involves stepwise coupling of amino acids using a protected amino acid resin, followed by deprotection and side-chain modifications. The synthesis is catalyzed by a variety of coupling agents and is typically carried out with high yield and selectivity.

What industries use AC-Ile-tyr-gly-glu-phe-NH2 (CAS: 168781-78-0)?

AC-Ile-tyr-gly-glu-phe-NH2 (CAS: 168781-78-0) is primarily used in the pharmaceutical industry for drug development, as it can serve as a model compound for studying peptide-based therapeutics. It is also used in the polymer industry for developing biodegradable materials and in the semiconductor industry for studying surface interactions.

What precautions should be taken when handling AC-Ile-tyr-gly-glu-phe-NH2 (CAS: 168781-78-0)?

When handling AC-Ile-tyr-gly-glu-phe-NH2 (CAS: 168781-78-0), it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. The compound should be stored in a cool, dry place and away from strong acids and bases. In case of a spill, the area should be ventilated and the spill cleaned up using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed safety information and emergency procedures.