2-Methyl-L-serine

Basic Information

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CAS Number

16820-18-1

Molecular Formula

C4H9NO3

Molecular Weight

119.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

286-288 ºC

Boiling Point

222.38°C (rough estimate)

Refractive Index

1.4183 (estimate)

Specific Rotation

3.3 º (c=5, 6N HCl 25 ºC)

SMILES

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CC(CO)(C(=O)O)N

InChI

InChI=1S/C4H9NO3/c1-4(5,2-6)3(7)8/h6H,2,5H2,1H3,(H,7,8)/t4-/m0/s1

InChIKey

CDUUKBXTEOFITR-BYPYZUCNSA-N

LogP

-1.2192999999999998

Topological Polar Surface Area

83.55 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

104

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-2-METHYLSERINE
2-METHYL-L-SERINE
AKOS015840233
CDUUKBXTEOFITR-BYPYZUCNSA-N
?-Methyl-L-serine
(S)-alpha-MeSer
NS00044834
L-Serine, 2-methyl-
(S)-2-AMINO-3-HYDROXY-2-METHYLPROPANOIC ACID
(S)-2-AMINO-2-METHYL-3-HYDROXYPROPANOIC ACID
alpha -Methyl-L-serine
MFCD00145243
alpha-Methylserine
Serine, 2-methyl-
SCHEMBL22925
CS-17329
AB03935
EW6
alpha-methyl serine
Q27144928
16820-18-1
CHEBI:74819
H-alpha-Me-Ser-OH
DTXSID80937461
(2S)-2-amino-3-hydroxy-2-methylpropanoic acid
PD196580
AC-2370
CS-W008467
A810948
(+)-2-Methyl-L-serine

MDL Number

MFCD00145243

Customs Code

29225000

FAQ

What are the physical and chemical properties of 2-Methyl-L-serine (CAS: 16820-18-1)?

2-Methyl-L-serine (CAS: 16820-18-1) is a crystalline compound with a molecular weight of 123.14 g/mol. It has a melting point of 165-166°C and is slightly soluble in water. This compound is reactive and can participate in condensation reactions and esterification reactions.

How is 2-Methyl-L-serine (CAS: 16820-18-1) typically synthesized?

2-Methyl-L-serine can be synthesized through the kinetic resolution of serine using chiral metal complexes as catalysts. The reaction typically involves the selective hydrolysis of a racemic mixture of serine, followed by the kinetic resolution step. This process yields a high enantiomeric excess and good yield.

What industries use 2-Methyl-L-serine (CAS: 16820-18-1)?

2-Methyl-L-serine is primarily used in pharmaceuticals for the synthesis of chiral compounds and as a building block in the production of biologically active molecules. It is also used in the development of certain polymers and as a reagent in analytical chemistry for sensor applications.

What precautions should be taken when handling 2-Methyl-L-serine (CAS: 16820-18-1)?

When handling 2-Methyl-L-serine (CAS: 16820-18-1), it is important to wear appropriate personal protective equipment (PPE), including gloves and a lab coat. The compound should be handled in a well-ventilated area, preferably in a fume hood. In case of a spill, it should be contained and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.