2-Amino-N-methylbenzenesulfonamide

Basic Information

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CAS Number

16288-77-0

Molecular Formula

C7H10N2O2S

Molecular Weight

186.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

59-60 ºC

Boiling Point

352.9°C at 760 mmHg

SMILES

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CNS(=O)(=O)C1=CC=CC=C1N

InChI

InChI=1S/C7H10N2O2S/c1-9-12(10,11)7-5-3-2-4-6(7)8/h2-5,9H,8H2,1H3

InChIKey

SSEZSHJJNNLTQI-UHFFFAOYSA-N

LogP

0.17689999999999995

Topological Polar Surface Area

72.19 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

232

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

CS-M2487
2-Amino-N-methyl-benzenesulfonamide
EN300-30706
2-amino-N-methylbenzene-1-sulfonamide
2-amino-N-methylbenzenesulfonamide
DTXSID70360623
SCHEMBL375689
2-amino-N -methyl-benzenesulfonamide
16288-77-0
SY168114
A882770
Benzenesulfonamide,2-amino-N-methyl-
GS-4448
N-Methyl 2-aminobenzenesulfonamide
MFCD04035388
AKOS000148266
AM20061135
o-N-Methylsulfamylanilin
FT-0645890
Z278052022
Benzenesulfonamide, 2-amino-N-methyl-
2-Amino-N-methylbenzenesulfonamide
2-amino-N-methylbenzenesulfonamide(SALTDATA: HCl)
N-Methyl 2-aMinobenzenesulfonaMide
N-Methyl-2-aminobenzenesulfonamide
SSEZSHJJNNLTQI-UHFFFAOYSA-N
BAS 05262676
STL411809
ZB

MDL Number

MFCD04035388

Customs Code

2935009090

FAQ

What are the physical and chemical properties of 2-Amino-N-methylbenzenesulfonamide (CAS: 16288-77-0)?

2-Amino-N-methylbenzenesulfonamide is a white crystalline solid with a molecular weight of approximately 229.23 g/mol. It is poorly soluble in water but soluble in organic solvents. Chemically, it is relatively stable but can react with strong acids or bases. It has a pKa of around 7.5 and is used in various chemical reactions due to its amine and sulfonamide functionalities.

How is 2-Amino-N-methylbenzenesulfonamide (CAS: 16288-77-0) typically synthesized?

2-Amino-N-methylbenzenesulfonamide is typically synthesized through the reaction of N-methylbenzenesulfonamide with ammonia. The reaction is carried out under mild conditions, and a mild acid catalyst such as hydrochloric acid is often used to promote the amide formation. The yield is generally high, and the product can be purified by recrystallization.

What industries use 2-Amino-N-methylbenzenesulfonamide (CAS: 16288-77-0)?

2-Amino-N-methylbenzenesulfonamide is used in industries such as pharmaceuticals, where it serves as an intermediate in the synthesis of drugs. It is also used in polymer science for the modification of polymers and in the development of sensors and semiconductors due to its functional groups.

What precautions should be taken when handling 2-Amino-N-methylbenzenesulfonamide (CAS: 16288-77-0)?

When handling 2-Amino-N-methylbenzenesulfonamide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a fume hood to minimize exposure. Spills should be cleaned up carefully, and the substance should be stored in a cool, dry place away from strong acids and bases. Safety data sheets (SDS) should always be consulted for detailed handling and storage information.