N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide | CAS No. 162401-30-1

N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide

Basic Information

CAS Number

162401-30-1

Molecular Formula

C14H8Cl2F4N2O3

Molecular Weight

399.13 g/mol

AD

Basic Physical Properties

C1=CC(=C(C=C1C(=O)NC2=C(C=NC=C2Cl)Cl)OC(F)F)OC(F)F

InChI

InChI=1S/C14H8Cl2F4N2O3/c15-7-4-21-5-8(16)11(7)22-12(23)6-1-2-9(24-13(17)18)10(3-6)25-14(19)20/h1-5,13-14H,(H,21,22,23)

InChIKey

OIYBMFARPXRQBW-UHFFFAOYSA-N

LogP

4.2654000000000005

Topological Polar Surface Area

63.68 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

440

Synonyms & References

English

  • 3,4-Bis(difluoromethoxy) Roflumilast
  • N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)benzaMide
  • N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy) benzamide
  • N-(3,5-Dichloropyrid-4-yl)-3,4-bis-difluoromethoxybenzamide
  • Roflumilast Impurity H
  • RofluMilast IMpurity 2
  • BenzaMide, N-(3,5-dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)-
  • DTXSID00599363
  • F19396
  • OIYBMFARPXRQBW-UHFFFAOYSA-N
  • N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide
  • 162401-30-1
  • A1-04253
  • A899355
  • Bis-difluoromethoxy Roflumilast impurity
  • SCHEMBL2889923
  • N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoromethoxy)benzamide

MDL Number

MFCD00938268

FAQ

What is N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide (CAS: 162401-30-1)?

N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide is a complex organic compound with a molecular structure that includes a pyridine ring and two difluoromethoxy groups attached to a benzene ring. It is characterized by its chlorine and fluorine substituents, which influence its physical and chemical properties.

What are the main uses of N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide (CAS: 162401-30-1)?

N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide is primarily used in the pharmaceutical industry as a precursor for drug synthesis. Its chemical properties make it suitable for developing antiviral and anti-inflammatory agents.

Is N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide (CAS: 162401-30-1) safe?

N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide is generally considered safe under proper handling and storage conditions. However, it can be irritating to the skin and eyes and may require appropriate personal protective equipment. Safe use includes wearing gloves and goggles, and avoiding inhalation or ingestion.

How should N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide (CAS: 162401-30-1) be stored?

N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture absorption and degradation. Storage temperature should be between 0°C and 25°C, and the container should be labeled with proper hazard information.

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