4-Chloro-6-(trifluoromethyl)-2-pyrimidinamine

Basic Information

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CAS Number

16097-60-2

Molecular Formula

C5H3ClF3N3

Molecular Weight

197.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

280.7°C at 760 mmHg

SMILES

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C1=C(N=C(N=C1Cl)N)C(F)(F)F

InChI

InChI=1S/C5H3ClF3N3/c6-3-1-2(5(7,8)9)11-4(10)12-3/h1H,(H2,10,11,12)

InChIKey

ZLIUVGFJXHOHLN-UHFFFAOYSA-N

LogP

1.731

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

163

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4-chloro-6-trifluoromethylpyrimidin-2-ylamine
2-Pyrimidinamine,4-chloro-6-(trifluoromethyl)-
SY018034
EN300-317190
AM20080437
AC-25692
2-Pyrimidinamine, 4-chloro-6-(trifluoromethyl)-
2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE
4-chloro-6-(trifluoromethyl)pyrimidin-2-amine
SB16109
2-amino-4-chloro-6-trifluoromethylpyrimidine
16097-60-2
4-chloro-6-trifluoromethylpyrimidine-2-amine
4-chloro-6-(trifluoromethyl)pyrimidine-2-amine
MFCD06656426
CS-W018916
J-507841
FT-0600091
A24638
DS-11147
AKOS006238097
SCHEMBL2396451
2-amino-4-chloro-6-(trifluoromethyl)pyrimidine
DTXSID60517740
2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine
4-Chloro-6-(Trifluoromethyl)Pyrimidin-2-Amine
PubChem16995
ZLIUVGFJXHOHLN-UHFFFAOYSA-N
FCH834194
RP25552
EN001078

MDL Number

MFCD06656426

Customs Code

2933599090

FAQ

What regulatory guidelines apply to 4-Chloro-6-(trifluoromethyl)-2-pyrimidinamine (CAS: 16097-60-2)?

4-Chloro-6-(trifluoromethyl)-2-pyrimidinamine (CAS: 16097-60-2) falls under various regulatory guidelines such as GHS (Global Harmonized System of Classification and Labeling of Chemicals) for classification and labeling, REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) for European Union regulations, and FDA/EPA requirements for use in pharmaceuticals and pesticides. The compound may also require specific handling and storage under OSHA standards and local environmental protection regulations.

Are there alternatives to 4-Chloro-6-(trifluoromethyl)-2-pyrimidinamine (CAS: 16097-60-2) in synthesis?

Several alternatives to 4-Chloro-6-(trifluoromethyl)-2-pyrimidinamine (CAS: 16097-60-2) exist in synthesis, including analogs like 4-fluoro-6-(trifluoromethyl)-2-pyrimidinamine and other pyrimidine derivatives. Alternative reagents such as 4-chloro-2-pyrimidinamine or 6-chloro-4-(trifluoromethyl)pyrimidin-2-amine can also be used, depending on the specific requirements of the reaction.

What is the market or research trend for 4-Chloro-6-(trifluoromethyl)-2-pyrimidinamine (CAS: 16097-60-2)?

The market and research trend for 4-Chloro-6-(trifluoromethyl)-2-pyrimidinamine (CAS: 16097-60-2) reflects increasing interest in its use as an intermediate in organic synthesis and as a precursor for pharmaceuticals and agrochemicals. Recent research has focused on its potential applications in antiviral and anticancer drug development, alongside ongoing studies on its environmental impact and biodegradability.

How should waste containing 4-Chloro-6-(trifluoromethyl)-2-pyrimidinamine (CAS: 16097-60-2) be handled?

Waste containing 4-Chloro-6-(trifluoromethyl)-2-pyrimidinamine (CAS: 16097-60-2) should be collected in appropriate containers and disposed of through professional waste disposal services to ensure safety and compliance. Incineration or chemical neutralization may be used, and environmental protection precautions should be followed, including proper labeling and documentation of waste management procedures to meet regulatory standards.