Basaglar | CAS No. 160337-95-1

Basaglar

Basic Information

CAS Number

160337-95-1

Molecular Formula

C267H404N72O78S2

Molecular Weight

6063 g/mol

AD

Basic Physical Properties

CCC(C)C1C(=O)NC2CSSCC(C(=O)NC(CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CO)CC(C)C)CC3=CC=C(C=C3)O)CCC(=O)N)CC(C)C)CCC(=O)O)CC(=O)N)CC4=CC=C(C=C4)O)C(=O)NCC(=O)O)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC5=CC=CC=C5)C(=O)NC(CC6=CC=CC=C6)C(=O)NC(CC7=CC=C(C=C7)O)C(=O)NC(C(C)O)C(=O)N8CCCC8C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)O)C(C)C)CC(C)C)CC9=CC=C(C=C9)O)CC(C)C)C)CCC(=O)O)C(C)C)CC(C)C)CC2=CNC=N2)CO)NC(=O)C(CC(C)C)NC(=O)C(CC2=CNC=N2)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C(C)C)NC(=O)C(CC2=CC=CC=C2)N)C(=O)NC(C(=O)NC(C(=O)N1)CO)C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C(C(C)CC)NC(=O)CN

InChI

InChI=1S/C267H404N72O78S6/c1-29-137(23)212(330-199(355)109-269)260(412)334-211(136(21)22)256(408)305-166(79-86-206(365)366)226(378)298-163(75-82-196(273)352)230(382)326-190-122-421-422-123-191-251(403)322-185(117-341)249(401)312-170(94-129(7)8)234(386)313-176(101-146-57-65-152(346)66-58-146)237(389)299-161(73-80-194(271)350)227(379)308-169(93-128(5)6)232(384)301-165(78-85-205(363)364)229(381)320-182(107-197(274)353)244(396)316-178(103-148-61-69-154(348)70-62-148)240(392)325-188(222(374)290-115-207(367)368)120-418-420-121-189(221(373)288-112-200(356)294-160(76-83-203(359)360)225(377)297-157(53-42-88-284-265(276)277)219(371)287-113-201(357)295-174(99-144-48-36-32-37-49-144)236(388)315-175(100-145-50-38-33-39-51-145)239(391)317-179(104-149-63-71-155(349)72-64-149)247(399)338-216(142(28)345)263(415)339-91-45-56-193(339)254(406)302-158(52-40-41-87-268)231(383)336-214(140(26)343)261(413)303-159(54-43-89-285-266(278)279)224(376)306-167(264(416)417)55-44-90-286-267(280)281)328-258(410)210(135(19)20)333-245(397)172(96-131(11)12)310-238(390)177(102-147-59-67-153(347)68-60-147)314-233(385)168(92-127(3)4)307-217(369)139(25)293-223(375)164(77-84-204(361)362)304-255(407)209(134(17)18)332-246(398)173(97-132(13)14)311-242(394)181(106-151-111-283-126-292-151)319-248(400)184(116-340)296-202(358)114-289-220(372)187(119-419-423-124-192(327-252(190)404)253(405)337-215(141(27)344)262(414)323-186(118-342)250(402)335-213(138(24)30-2)259(411)329-191)324-235(387)171(95-130(9)10)309-241(393)180(105-150-110-282-125-291-150)318-228(380)162(74-81-195(272)351)300-243(395)183(108-198(275)354)321-257(409)208(133(15)16)331-218(370)156(270)98-143-46-34-31-35-47-143/h31-39,46-51,57-72,110-111,125-142,156-193,208-216,340-349H,29-30,40-45,52-56,73-109,112-124,268-270H2,1-28H3,(H2,271,350)(H2,272,351)(H2,273,352)(H2,274,353)(H2,275,354)(H,282,291)(H,283,292)(H,287,371)(H,288,373)(H,289,372)(H,290,374)(H,293,375)(H,294,356)(H,295,357)(H,296,358)(H,297,377)(H,298,378)(H,299,389)(H,300,395)(H,301,384)(H,302,406)(H,303,413)(H,304,407)(H,305,408)(H,306,376)(H,307,369)(H,308,379)(H,309,393)(H,310,390)(H,311,394)(H,312,401)(H,313,386)(H,314,385)(H,315,388)(H,316,396)(H,317,391)(H,318,380)(H,319,400)(H,320,381)(H,321,409)(H,322,403)(H,323,414)(H,324,387)(H,325,392)(H,326,382)(H,327,404)(H,328,410)(H,329,411)(H,330,355)(H,331,370)(H,332,398)(H,333,397)(H,334,412)(H,335,402)(H,336,383)(H,337,405)(H,338,399)(H,359,360)(H,361,362)(H,363,364)(H,365,366)(H,367,368)(H,416,417)(H4,276,277,284)(H4,278,279,285)(H4,280,281,286)/t137-,138-,139-,140+,141+,142+,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,187-,188-,189-,190-,191-,192-,193-,208-,209-,210-,211-,212-,213-,214-,215-,216-/m0/s1

InChIKey

COCFEDIXXNGUNL-RFKWWTKHSA-N

LogP

-21.12019000000025

Topological Polar Surface Area

2437.980000000002 Ų

Hydrogen Bond Donor/Acceptor

96 / 150

Complexity

15300

Synonyms & References

English

  • SoloStar
  • HOE 71GT
  • Insulin glargine
  • Basaglar
  • 21(sup A)-Glycine-30(sup B)a-L-arginine-30(sup B)b-L-arginine insulin (human)
  • 21(sup A)-glycine-30(supp B)a-L-arginine-30(supp B)b-L-arginineinsulin (human)
  • Optisulin
  • Toujeo Solostar
  • Lusduna Nexvue
  • Lantus R
  • SoloStar [Insulin delivery pen]
  • UNII-2ZM8CX04RZ
  • A21-Gly-B31-Arg-B32-Arg-insulin
  • Toujeo
  • Insulin, glycyl(A21)-arginyl(B31,B32)-
  • LY 2963016
  • Lantus Solostar
  • 2ZM8CX04RZ
  • 160337-95-1
  • Glargine
  • Insulin (human), 21(sup A)-glycine-30(sup B)a-L-arginine-30(sup B)b-L-arginine-
  • MK-1293
  • HOE 901
  • Insulin glargine [USAN:INN:BAN]
  • Insulin (human),21A-glycine-30Ba-Larginine- 30Bb-L-arginine-
  • INSULIN GLARGINE
  • Insulin glargine [INN:BAN]
  • Lantus
  • Solostar
  • Unii-2zm8cx04rz
  • Solostar [insulin delivery pen]

FAQ

What regulatory guidelines apply to Basaglar (CAS: 160337-95-1)?

Basaglar (CAS: 160337-95-1) is subject to the Global Harmonized System (GHS) for classification and labeling of chemicals, REACH regulations for European markets, and FDA/EPA guidelines for pharmaceutical and chemical applications. Manufacturers must comply with these regulations for safety data sheets, labeling, and environmental handling.

Are there alternatives to Basaglar (CAS: 160337-95-1) in synthesis?

While Basaglar (CAS: 160337-95-1) is a specific compound, in synthesis, alternatives like glargine, insulin detemir, and insulin glulisine can be considered. These alternatives may offer similar properties but with different chemical structures and synthesis methods.

What is the market or research trend for Basaglar (CAS: 160337-95-1)?

The market for Basaglar (CAS: 160337-95-1) is growing due to its long-lasting effects in managing blood glucose levels. Research trends focus on improving formulations, understanding long-term safety, and exploring combination therapies. The market is expected to expand with increasing diabetes prevalence and advancements in insulin delivery systems.

How should waste containing Basaglar (CAS: 160337-95-1) be handled?

Waste containing Basaglar (CAS: 160337-95-1) should be collected in appropriate containers and disposed of through regulated medical waste channels. This includes incineration or professional waste disposal services to ensure safety and compliance with environmental regulations. Proper labeling and documentation are required for safe transportation and disposal.

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