N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanine | CAS No. 1599440-15-9

N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanine

Basic Information

CAS Number

1599440-15-9

Molecular Formula

C23H28N4O7

Molecular Weight

472.5 g/mol

AD

Basic Physical Properties

OC(=O)[C@H](CC1C=CC=CC=1)NC(=O)CNC(=O)CNC(=O)CCCCCN1C(=O)C=CC1=O

InChI

InChI=1S/C23H28N4O7/c28-18(9-5-2-6-12-27-21(31)10-11-22(27)32)24-14-19(29)25-15-20(30)26-17(23(33)34)13-16-7-3-1-4-8-16/h1,3-4,7-8,10-11,17H,2,5-6,9,12-15H2,(H,24,28)(H,25,29)(H,26,30)(H,33,34)/t17-/m0/s1

InChIKey

NFVPAFLSJIPUCL-KRWDZBQOSA-N

LogP

-0.48369999999999713

Topological Polar Surface Area

161.98 Ų

Hydrogen Bond Donor/Acceptor

4 / 11

Complexity

787

Synonyms & References

English

  • MC-Gly-Gly-Phe

MDL Number

MFCD32690114

FAQ

What are the physical and chemical properties of N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanine (CAS: 1599440-15-9)?

N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanine (CAS: 1599440-15-9) is a crystalline compound with a molecular weight of approximately 556.58 g/mol. It is sparingly soluble in water but soluble in organic solvents like methanol and ethanol. This compound is relatively stable under normal conditions but may react with strong bases or reducing agents. It is often used in pharmaceutical research and synthesis due to its unique structural features.

How is N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanine (CAS: 1599440-15-9) typically synthesized?

N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanine is typically synthesized through multi-step organic synthesis processes involving acylation, amidation, and coupling reactions. Commonly used catalysts include acids such as trifluoroacetic acid. The overall yield is moderate, around 50-70%, and the purity is generally high if the reaction conditions are carefully controlled.

What industries use N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanine (CAS: 1599440-15-9)?

N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanine (CAS: 1599440-15-9) is primarily used in the pharmaceutical industry for medicinal chemistry and drug development. It is also of interest in polymer science for its potential use in biodegradable materials and in sensor applications due to its unique chemical structure and properties.

What precautions should be taken when handling N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanine (CAS: 1599440-15-9)?

When handling N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanine (CAS: 1599440-15-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be carried out in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly washed with water. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.

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