4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol | CAS No. 15942-05-9

4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol

Basic Information

CAS Number

15942-05-9

Molecular Formula

C13H19Br2ClN2O

Molecular Weight

414.56 g/mol

AD

Basic Physical Properties

C1CC(CCC1NCC2=C(C(=CC(=C2)Br)Br)N)O.Cl

InChI

InChI=1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H

InChIKey

QNVKOSLOVOTXKF-UHFFFAOYSA-N

LogP

3.6087000000000025

Topological Polar Surface Area

58.28 Ų

Hydrogen Bond Donor/Acceptor

4 / 3

Synonyms & References

English

  • AMBROXOL HYDROCHLORIDE
  • AMBROXOL HCL
  • AMBROXOLHYDROCLORIDE
  • MUCOSOLVAN

MDL Number

MFCD00078932

FAQ

What are the physical and chemical properties of 4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol (CAS: 15942-05-9)?

4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol is a crystalline solid with a molecular weight of approximately 495.3 g/mol. It has a low water solubility and is slightly soluble in polar solvents. This compound exhibits limited reactivity under normal conditions, but caution is advised due to the presence of bromine substituents.

How is 4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol (CAS: 15942-05-9) typically synthesized?

4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol can be synthesized through a multi-step process involving the coupling of 2-amino-3,5-dibromobenzyl chloride with cyclohexanol in the presence of a base. Commonly, potassium carbonate is used as the base, and the reaction is carried out in an aprotic solvent like dimethylformamide (DMF). The final product is obtained through recrystallization.

What industries use 4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol (CAS: 15942-05-9)?

4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol finds application in the pharmaceutical industry due to its potential use as a precursor in the synthesis of biologically active compounds. It is also utilized in the development of sensors due to its unique chemical properties.

What precautions should be taken when handling 4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol (CAS: 15942-05-9)?

When handling 4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat is essential. The compound should be stored in a well-ventilated area and handled under a fume hood. In case of spillage, immediately clean up using appropriate methods and consult a safety data sheet (SDS) for detailed instructions.

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