Apixaban Impurity 82

Basic Information

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CAS Number

1575-61-7

Molecular Formula

C5H8Cl2O

Molecular Weight

155.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

38-39 °C/0.15 mmHg

Refractive Index

n20/D 1.464(lit.)

SMILES

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C(CCCl)CC(=O)Cl

InChI

InChI=1S/C5H8Cl2O/c6-4-2-1-3-5(7)8/h1-4H2

InChIKey

SVNNWKWHLOJLOK-UHFFFAOYSA-N

LogP

2.1609

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

72.8

Safety Information

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GHS Hazard Pictograms

H302

H314

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Explosive Limit

2.0-10.2%(V)

Synonyms & References

English

1575-61-7
MFCD00000758
4-02-00-00881 (Beilstein Handbook Reference)
FT-0620345
W-108002
NSC 84182
SVNNWKWHLOJLOK-UHFFFAOYSA-N
BRN 1745182
5-Chlorovaleroyl chloride, purum, >=97.0% (T)
A809852
NS00007061
5-Chlorovalerylchloride
5-Chloro-valeroyl chloride
WLN: GV4G
5-Chlorovaleroyl chloride
5-chloro-pentanoyl chloride
EN300-36082
5-Chloropentanoyl chloride
Pentanoyl chloride, 5-chloro-
2-chloroethylpropionyl chloride
CS-0015913
D89459
EINECS 216-403-1
AKOS009156765
chlorovaleryl chloride
5-chlorovaleric acid chloride
DTXSID60166272
delta-chlorovaleryl chloride
SCHEMBL77065
delta-chlorovaleric acid chloride
C1789

MDL Number

MFCD00000758

Customs Code

2915900090

FAQ

What is Apixaban Impurity 82 (CAS: 1575-61-7)?

Apixaban Impurity 82 (CAS: 1575-61-7) is a pharmaceutical byproduct associated with the synthesis of apixaban, an anticoagulant drug. It typically exhibits specific chemical properties, such as solubility in organic solvents and a defined molecular structure. This impurity is often analyzed to ensure drug purity and compliance with quality standards in pharmaceutical manufacturing.

What are the main uses of Apixaban Impurity 82 (CAS: 1575-61-7)?

Apixaban Impurity 82 (CAS: 1575-61-7) is primarily used in pharmaceutical research for impurity profiling, drug development, and quality control processes. It plays a critical role in analytical methods to identify and quantify trace contaminants during the production of apixaban, aiding in regulatory compliance and ensuring patient safety.

Is Apixaban Impurity 82 (CAS: 1575-61-7) safe?

Apixaban Impurity 82 (CAS: 1575-61-7) is generally considered safe when handled under controlled laboratory conditions. However, as with many chemical impurities, it requires appropriate protective measures, such as gloves and ventilation, to minimize exposure. Safety data may be limited, so adherence to standard chemical handling protocols is recommended.

How should Apixaban Impurity 82 (CAS: 1575-61-7) be stored?

Apixaban Impurity 82 (CAS: 1575-61-7) should be stored in a cool, dry place, protected from light, and in airtight containers to maintain stability. It is sensitive to moisture and heat, so storage under inert gas or in a desiccator may be necessary to preserve its chemical integrity over time.