Carmustine | CAS No. 154-93-8

Carmustine

Basic Information

CAS Number

154-93-8

Molecular Formula

C5H9Cl2N3O2

Molecular Weight

214.05 g/mol

AD

Basic Physical Properties

Melting Point

30 °C

Boiling Point

404

Water Solubility

<0.1 g/100 mL at 18 ºC

Refractive Index

1.6100 (estimate)

C(CCl)NC(=O)N(CCCl)N=O

InChI

InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)

InChIKey

DLGOEMSEDOSKAD-UHFFFAOYSA-N

LogP

1.157

Topological Polar Surface Area

61.77 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

156

Safety Information

View Safety Information

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral
H341 Suspected of causing genetic defects
Germ cell mutagenicity
H350 May cause cancer
Carcinogenicity
H360 May damage fertility or the unborn child
Reproductive toxicity
H370 Causes damage to organs
Specific target organ toxicity, single exposure
H372 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

Hazard Class

Class 6.1 Class 6.1

Toxicity

LD50 in mice (mg/kg): 19-25 orally, 26 i.p., 24 s.c.; in rats (mg/kg): 30-34 orally (Thompson, Larson)

Synonyms & References

English

  • DB00262
  • NCGC00260873-01
  • N,N'-BIS(2-CHLOROETHYL)-N-NITROSOUREA
  • bis(chloroethyl) nitrosourea
  • Gliadel (TN)
  • CARMUSTINE [WHO-DD]
  • W-108025
  • EU-0100188
  • DTI-015
  • CARMUSTINE [USP-RS]
  • Carmustine (98%)
  • Urea, N,N'-bis(2-chloroethyl)-N-nitroso-
  • DivK1c_000835
  • Carustine
  • Urea,3-bis(2-chloroethyl)-1-nitroso-
  • Bischloroethyl nitrosourea [Chloroethyl nitrosoureas]
  • LP00188
  • NSC 409962
  • NS00005564
  • KBioGR_001296
  • BiCNU (TN)
  • Becenun
  • Bischlorethylnitrosourea
  • Nitrourean
  • Carmustine [USAN:USP:INN:BAN]
  • NCGC00015204-02
  • CARMUSTINE [USAN]
  • BDBM50015950
  • AB00052431-07
  • SRI 1720
  • CARMUSTINE [HSDB]

MDL Number

MFCD00057706

Customs Code

2924199090

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