3,4-Dimethoxybenzamide

Basic Information

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CAS Number

1521-41-1

Molecular Formula

C9H11NO3

Molecular Weight

181.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

163-164 ºC

Boiling Point

278.4±25.0 ºC (760 Torr),

Flash Point

126.1±19.5 ºC,

Refractive Index

1.534

SMILES

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COC1=C(C=C(C=C1)C(=O)N)OC

InChI

InChI=1S/C9H11NO3/c1-12-7-4-3-6(9(10)11)5-8(7)13-2/h3-5H,1-2H3,(H2,10,11)

InChIKey

XNDZRGTVUVVHQT-UHFFFAOYSA-N

LogP

0.8027

Topological Polar Surface Area

61.55 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

184

Synonyms & References

English

NS00024960
SCHEMBL335681
AS-57779
SY275554
NSC-370837
CHEMBL505584
FT-0656647
A809265
3-10-00-01427 (Beilstein Handbook Reference)
Veratramide
1521-41-1
Veratrimidic acid
AKOS000593686
Benzamide, 3,4-dimethoxy-
Oprea1_176663
Z33546772
XNDZRGTVUVVHQT-UHFFFAOYSA-N
UNII-SEW9F1FKI8
3,4-Dimethoxybenzamide
MFCD00017128
NSC 370837
Veratramide; Veratrimidic acid; 3,4-Dimethoxybenzamide; NSC 370837
DTXSID1074549
SR-4191
SEW9F1FKI8
EINECS 216-190-5
Oprea1_802187
J-511211
NSC370837
BRN 2646714
AMY28152

MDL Number

MFCD00017128

Customs Code

2924299090

FAQ

What are the physical and chemical properties of 3,4-Dimethoxybenzamide (CAS: 1521-41-1)?

3,4-Dimethoxybenzamide (CAS: 1521-41-1) is a white crystalline solid with a molecular weight of approximately 184.19 g/mol. It has a solubility of about 50 mg/mL in water and is soluble in organic solvents like methanol and ethanol. It is stable under normal conditions but can react with strong acids and bases. The compound is not flammable but requires proper handling to avoid potential hazards.

How is 3,4-Dimethoxybenzamide (CAS: 1521-41-1) typically synthesized?

3,4-Dimethoxybenzamide is typically synthesized by the reaction of p-dimethoxybenzoyl chloride with an amine. Common amine substrates include methylamine and ethylamine. The reaction is usually carried out in a solvent such as dichloromethane, with the use of a catalyst like 4-dimethylaminopyridine (DMAP) to improve yield and selectivity. The product is obtained in moderate to good yield, making this method suitable for both academic and industrial applications.

What industries use 3,4-Dimethoxybenzamide (CAS: 1521-41-1)?

3,4-Dimethoxybenzamide (CAS: 1521-41-1) finds applications in various industries. It is used in pharmaceuticals as a precursor for drug synthesis, in polymers as a stabilizer, and in sensors for its reactivity. Additionally, it is utilized in the semiconductor industry for its electronic properties. Due to its versatility, it is a valuable compound in these fields.

What precautions should be taken when handling 3,4-Dimethoxybenzamide (CAS: 1521-41-1)?

When handling 3,4-Dimethoxybenzamide (CAS: 1521-41-1), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be immediately contained and cleaned up using suitable absorbents. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and follow all local regulations and guidelines for safe handling and disposal.