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5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine | CAS No. 150780-67-9

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine

Basic Information

Chemical_Structure_Of
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CAS Number

150780-67-9

Molecular Formula

C45H56N7O9P

Molecular Weight

869.9 g/mol

AD

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids
Basic Chemical Raw Materials Organic Chemicals Ethers
Basic Chemical Raw Materials Organic Chemicals Nitriles
Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds
Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates
Fine Chemicals Dyes and Pigments Organic Dyes
Fine Chemicals Surfactants Anionic Surfactants
Agricultural Chemicals Pesticides Insecticides
Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OC

InChI

InChI=1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(61-62(59-25-13-24-46)52(29(3)4)30(5)6)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1

InChIKey

IRRDHRZUOZNWDJ-MLLDKZSOSA-N

LogP

8.37538

Complexity

1490

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • DMT-2'-O-methyl-rG(Ib) Phosphoramidite
  • MFCD00792625
  • DMT-2'O-Methyl-rG(ib) Phosphoramidite, configured for MerMade
  • 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • 5/'-O-(4,4-Dimethoxytrityl)-2/'-O-methyl-N-isobutyrylguanosine-3/'-(2-cyanoethyl-N,N-diisopropyl)pho
  • N-{9-[(2R,3R,4R,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-3-methoxyoxolan-2-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-2-methylpropanamide
  • 2??-OMe-G(ibu) Phosphoramidite
  • J-700113
  • 150780-67-9
  • 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-(2-cyanoethyl diisopropylphosphoramidite)
  • BP-40047
  • DMT-2'O-Methyl-rG(ib) Phosphoramidite
  • (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
  • 5'-O-(4,4- paragraph signthorn(1/4)xNo>>uEy+/-(1/2)(1/4)x>>u)-2'-O-(1/4)x>>u-N-Oi paragraph sign inverted exclamation marko pound>>uAnUO-3'-(2-Ce>>uOO>>u-N,N- paragraph signthornOi+/-u>>u)NCAxo pound degrees .
  • N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • DMT-2'O-Methyl-rG(ib) Phosphoramidite, configured for ABI
  • DMT-2'O-Methyl-rG(ib) Phosphoramidite, configured for ABI, configured for (??KTA(R) and OligoPilot(R))
  • CS-0159225
  • DMT-2'O-Methyl-rG(ib) Phosphoramidite, configured for ??KTA(R) and OligoPilot(R)
  • 2'-OMe-ibu-GPhosphoramidite
  • A852128
  • 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-O-methyl-N-(2-methylpropanoyl)guanosine
  • 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;(2S,3S,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydropurin-9-yl)-4-methoxy-tetrahydrofuran-3-yl 2-cy
  • N-{9-[(2R,3R,4R,5R)-5-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-4-{[(2-CYANOETHOXY)(DIISOPROPYLAMINO)PHOSPHANYL]OXY}-3-METHOXYOXOLAN-2-YL]-6-OXO-1H-PURIN-2-YL}-2-METHYLPROPANAMIDE
  • N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
  • 2'-OMe-G(ibu) Phosphoramidite
  • 2'-OMe-ibu-G Phosphoramidite
  • 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
  • 2'-OMe-G(iBu)-3'-phosphoramidite
  • AC-32378

MDL Number

MFCD00792625

FAQ

What is 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine (CAS: 150780-67-9)?
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine (CAS: 150780-67-9) is a complex nucleoside analog. It features a unique structure with a phosphorothioate linkage and a specific isobutyryl modification. This compound is used in pharmaceutical research and development.

What are the main uses of 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine (CAS: 150780-67-9)?
The main uses of this compound include as an intermediate in the synthesis of nucleoside analogs and potential drug candidates. It is also utilized in research for antiviral and anticancer applications.

Is 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine (CAS: 150780-67-9) safe?
The safety of 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine (CAS: 150780-67-9) depends on its intended use. Proper handling and storage are crucial. It should be kept away from fire, heat, and strong oxidizers. Protective clothing and eyewear must be worn during handling.

How should 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine (CAS: 150780-67-9) be stored?
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine (CAS: 150780-67-9) should be stored in a cool, dry place, protected from light. It should be kept in a tightly sealed container to prevent degradation. The storage temperature should be below 25°C, and the container should be away from any sources of heat or ignition sources.

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Supplier Information

Nanjing Ancient Core Biotechnology Co., Ltd.

CAS Number: 150780-67-9

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5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine — Shanghai Titan Shareholding Technology Co., Ltd.

Shanghai Titan Shareholding Technology Co., Ltd.

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5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine — ShenZhenAiTaHuaXue Co Ltd

ShenZhenAiTaHuaXue Co Ltd

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Jiangsu Rufen Synthetic Technology Co., Ltd.

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5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine — Leyan Reagents

Leyan Reagents

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5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine — ShangHaiJiZhiShengHua Technology Co Ltd

ShangHaiJiZhiShengHua Technology Co Ltd

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5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine — Jin Jinle (Hunan) Chemical Co., Ltd.

Jin Jinle (Hunan) Chemical Co., Ltd.

CAS Number: 150780-67-9

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5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine — ShangHaiMaiRuiErShengHua Technology Co Ltd

ShangHaiMaiRuiErShengHua Technology Co Ltd

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5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine — Beijing Bailingwei Technology Co., Ltd.

Beijing Bailingwei Technology Co., Ltd.

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ShangHaiZhenZhun Biotechnology Co Ltd

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MaAnShanZhiYanShengWuYiYao Technology Co Ltd

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Shanghai Kewei Chemical Technology Co., Ltd.

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ShangHaiXiangGengKeJi Development Co Ltd

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Shanghai Kezuo Yongxin Biological Technology Co., Ltd.

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