2-Fluoroadenosine

Basic Information

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CAS Number

146-78-1

Molecular Formula

C10H12FN5O4

Molecular Weight

285.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

200°C

Refractive Index

-72 ° (C=0.1, EtOH)

Specific Rotation

-67 ~ -61° (c=1, DMSO)

SMILES

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C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)F)N

InChI

InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1

InChIKey

HBUBKKRHXORPQB-UUOKFMHZSA-N

LogP

-1.8408999999999995

Topological Polar Surface Area

139.54 Å²

Hydrogen Bond Donor/Acceptor

5 / 9

Complexity

367

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

0S67290CRJ
BCP0726000182
ADENOSINE, 2-FLUORO-
2FA
CHEBI:39740
SMR000471849
SRI 727
MLS001066367
SCHEMBL977919
NSC 30605
2-Fas
AC-22363
MFCD00866394
PD016313
2-FLUORO-9-.BETA.-D-RIBOFURANOSYLADENINE
NSC-30605
UNII-0S67290CRJ
AKOS015853307
AI3-52599
DTXSID70163252
BDBM50118807
BP-58636
4-26-00-03723 (Beilstein Handbook Reference)
NCGC00181336-02
BRD-K72238567-001-12-4
(2R,3R,4S,5R)-2-(6-amino-2-fluoro-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;(2R,3R,4S,5R)-2-(6-Amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
2-Fluoroadenosine
2-FluoroAdo
cid_8975
HMS2231E03
AM84420

MDL Number

MFCD00866394

FAQ

What is 2-Fluoroadenosine (CAS: 146-78-1)?

2-Fluoroadenosine is a chemical compound with the CAS number 146-78-1. It is a purine nucleoside derivative with a fluoro group attached at position 2 of the adenosine structure. This compound is less stable and has different biological properties compared to adenosine.

What are the main uses of 2-Fluoroadenosine (CAS: 146-78-1)?

2-Fluoroadenosine is primarily used in pharmaceutical research for studying the effects of fluorine-substituted nucleosides on biological systems. It is also used in the development of potential therapeutics targeting purine metabolism.

Is 2-Fluoroadeninesine (CAS: 146-78-1) safe?

2-Fluoroadenosine (CAS: 146-78-1) is generally considered safe for laboratory use when handled with proper precautions. However, it should be used in a well-ventilated area and with appropriate personal protective equipment (PPE), as it may be toxic if ingested or inhaled. It is important to follow all safety guidelines provided by the manufacturer.

How should 2-Fluoroadenosine (CAS: 146-78-1) be stored?

2-Fluoroadenosine (CAS: 146-78-1) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation and ensure purity. Avoid exposing it to moisture and maintain a temperature below 25°C for optimal stability.