2,4-Dimethyl-8-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one

Basic Information

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CAS Number

145733-36-4

Molecular Formula

C23H21N7O

Molecular Weight

411.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

197-199°

Boiling Point

759.4±70.0°C at 760 mmHg

SMILES

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CC1=C2CCC(=O)N(C2=NC(=N1)C)CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5

InChI

InChI=1S/C23H21N7O/c1-14-18-11-12-21(31)30(23(18)25-15(2)24-14)13-16-7-9-17(10-8-16)19-5-3-4-6-20(19)22-26-28-29-27-22/h3-10H,11-13H2,1-2H3,(H,26,27,28,29)

InChIKey

ADXGNEYLLLSOAR-UHFFFAOYSA-N

LogP

3.4199400000000013

Topological Polar Surface Area

100.55000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 8

Complexity

625

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

AKOS016011082
EX-A082
8-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2,4-dimethyl-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one
Tasosartan (USAN/INN)
AC-35374
CS-0017594
L001443
2,4-Dimethyl-8-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one
Q1317131
UNII-48G92V856H
Pyrido[2,3-d]pyrimidin-7(6H)-one, 5,8-dihydro-2,4-dimethyl-8-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
ETHYLGLYCIDYLETHER
NS00070844
AMY31168
5,8-Dihydro-2,4-dimethyl-8-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)pyrido(2,3-d)pyrimidin-7(6H)-one
2,4-dimethyl-8-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-5,8-dihydro-6H-pyrido[2,3-d]pyrimidin-7-one
J-524315
Tasosartan [USAN:INN:BAN]
WAY-126756
FT-0631174
HY-A0250
GTPL6898
TASOSARTAN [MI]
5,8-dihydro-2,4-dimethyl-8-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]pyrido[2,3-d]pyrimidin-7(6H)-one
CHEBI:135666
TASOSARTAN [MART.]
TASOSARTAN
145733-36-4
taso-sartan
ANA756
CHEMBL432162

MDL Number

MFCD00865905

FAQ

What is 2,4-Dimethyl-8-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one (CAS: 145733-36-4)?

2,4-Dimethyl-8-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one is a synthetic organic compound with a complex structure. It is characterized by its specific molecular composition and unique chemical properties. This compound is often used in pharmaceutical research and development for its potential medicinal applications.

What are the main uses of 2,4-Dimethyl-8-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one (CAS: 145733-36-4)?

2,4-Dimethyl-8-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one primarily serves as a precursor in the synthesis of pharmaceutical compounds. It is also used in the development of new drugs for various medical conditions, including cancer and inflammation.

Is 2,4-Dimethyl-8-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one (CAS: 145733-36-4) safe?

2,4-Dimethyl-8-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one is generally safe when handled properly. However, it is important to follow all safety guidelines, including proper ventilation, protective clothing, and the use of appropriate personal protective equipment. Avoid contact with skin and eyes, and do not inhale any dust or fumes.

How should 2,4-Dimethyl-8-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one (CAS: 145733-36-4) be stored?

2,4-Dimethyl-8-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture and contamination. Proper storage conditions are essential to maintain its stability and reactivity.