N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide

Basic Information

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CAS Number

145701-23-1

Molecular Formula

C12H8F3N5O3S

Molecular Weight

359.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

220-221° (dec) (Van Heertum); also reported as 193.5-230.5° (Thompson)

Density

1.7500

Refractive Index

1.676

SMILES

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COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F

InChI

InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3

InChIKey

QZXATCCPQKOEIH-UHFFFAOYSA-N

LogP

1.3509999999999995

pKa

4.54(at 25℃)

Topological Polar Surface Area

98.47999999999999 Å²

Hydrogen Bond Donor/Acceptor

1 / 8

Complexity

541

Safety Information

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GHS Hazard Pictograms

H410

Hazard Statement

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Toxicity

LD50 in rat, quail (mg/kg): >6000, 1046 orally; percutaneously in rabbit: >2000 mg/kg; LC50 in rainbow trout, bluegill (96 hr): >96, >98 mg/l (Thompson)

Synonyms & References

English

00A64ZX8NB
Q22807578
N-(2,6-difluorophenyl)-5-methoxy-8-fluoro-(1,2,4)-triazolo-(1,5c)-pyrimidine-2-sulfonamide
N-(2,6-DIFLUOROPHENYL)-8-FLUORO-5-METHOXY(1,2,4)TRIAZOLO(1,5-C)PYRIMIDINE-2-SULFONAMIDE
N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide
NIKOS
[1,2,4]Triazolo[1,5-c]pyrimidine-2-sulfonamide, N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-
AMY12231
CHEMBL3185236
DS-6608
J-008140
QZXATCCPQKOEIH-UHFFFAOYSA-N
AKOS015901201
NCGC00255762-01
Florasulam, PESTANAL(R), analytical standard
NS00001447
(1,2,4)TRIAZOLO(1,5-C)PYRIMIDINE-2-SULFONAMIDE, N-(2,6-DIFLUOROPHENYL)-8-FLUORO-5-METHOXY-
CAS-145701-23-1
2',6',8-TRIFLUORO-5-METHOXY(1,2,4)TRIAZOLO(1,5-C)PYRIMIDINE-2-SULFONANILIDE
N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide
A884585
A1-01909
Kantor
Tox21_302433
DB15316
CS-0013914
Florasulam 10 microg/mL in Acetonitrile
HSDB 7941
Primus
UNII-00A64ZX8NB
Kantor; Primus; Primus SC

MDL Number

MFCD08273843

FAQ

What is N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide (CAS: 145701-23-1)?

N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide is a chemical compound with the CAS number 145701-23-1. It is a complex organic molecule with a unique structure, including a triazole ring, a pyrimidine ring, and a sulfonamide group. This compound has a molecular formula of C14H10F3N5O2S.

What are the main uses of N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide (CAS: 145701-23-1)?

N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide is primarily used in pharmaceutical research and development. It is a potential therapeutic agent with antiviral and anticancer properties. Additionally, it can be used in various biological studies due to its unique chemical structure.

Is N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide (CAS: 145701-23-1) safe?

N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide is generally considered safe for laboratory use when handled with appropriate protective measures. However, it is important to follow all safety guidelines, including wearing appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Ensure good ventilation and avoid inhaling the compound or its fumes. Handling should be done in a well-ventilated area or a fume hood.

How should N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide (CAS: 145701-23-1) be stored?

N-(2,6-Difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide should be stored in a cool, dry place, preferably at a temperature range of 15-25°C. It should be kept away from sources of heat and direct sunlight. The compound should be stored in a tightly sealed container to prevent exposure to air and moisture. Take care to keep it away from incompatible materials, such as strong oxidizers or acids, to minimize the risk of chemical reactions. Store in a secure place where unauthorized individuals cannot access it. Compliance with local regulations and safety standards is essential for proper storage and handling.