![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
5-{4-[2-(5-Ethyl-1-oxido-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione | CAS No. 145350-09-0
5-{4-[2-(5-Ethyl-1-oxido-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
Basic Information
CAS Number
145350-09-0
Molecular Formula
C19H20N2O4S
Molecular Weight
372.4 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
158-160°C
Safety Information
View Safety InformationHazard Statement
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- PioglitazoneN-Oxide
- YTKQAGFCVMHNHM-UHFFFAOYSA-N
- rac-2-(2-{4-[(2,4-dioxothiazolidin-5-yl)methyl]phenoxy}ethyl)-5-ethylpyridine-1-oxide
- 2-(2-(4-((2,4-dioxothiazolidin-5-yl)methyl)phenoxy)ethyl)-5-ethylpyridine 1-oxide
- SCHEMBL9545736
- AKOS030255781
- A909414
- Pioglitazone N-Oxide
- Pioglitazone-d4 N-Oxide (deuterated)
- 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-1-oxido-2-pyridinyl)ethoxy]phenyl]methyl]-
- AS-18997
- FT-0673908
- J-008091
- 5-[[4-[2-(5-Ethyl-1-oxido-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione; 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, N-oxide; Pioglitazone N-oxide
- 5-[[4-[2-(5-ethyl-1-oxidopyridin-1-ium-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
- 145350-09-0
- DTXSID30443587
- Pioglitazone Hydrochloride
- Pioglitazone HCl
- 2-(2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)ethyl)-5-ethylpyridine 1-oxide
MDL Number
MFCD00915839
Customs Code
2933990090
FAQ
What regulatory guidelines apply to 5-{4-[2-(5-Ethyl-1-oxido-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione (CAS: 145350-09-0)?
This compound, CAS 145350-09-0, is subject to various regulatory guidelines such as GHS classification, which mandates the use of specific hazard labels and safety data sheets. For manufacturing and import/export, REACH regulations in the EU require registration and reporting of substances above one tonne per year. FDA/EPA guidelines may apply for pharmaceutical and environmental concerns respectively.
Are there alternatives to 5-{4-[2-(5-Ethyl-1-oxido-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione (CAS: 145350-09-0) in synthesis?
In synthesis, alternatives to this compound include other thiazolidine derivatives with similar functional groups, such as ethyl 5-(4-{[2-(5-ethyl-2-pyridyl)ethoxy]methyl}-1,3-thiazolidin-2-ylidene)hydantoin. Isomers and analogs can also be considered based on specific application requirements and availability.
What is the market or research trend for 5-{4-[2-(5-Ethyl-1-oxido-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione (CAS: 145350-09-0)?
The market for this compound is expanding in pharmaceutical applications due to its potential as a bioisostere in drug design. Research trends indicate increasing interest in its use as a lead compound for developing anti-inflammatory and antiviral drugs. Market analysis suggests growing demand driven by emerging studies highlighting its biological activity.
How should waste containing 5-{4-[2-(5-Ethyl-1-oxido-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione (CAS: 145350-09-0) be handled?
Waste containing this compound should be collected and stored in sealed containers to prevent environmental contamination. Proper incineration or professional waste disposal services should be utilized, adhering to local and international environmental regulations. Precautions include ensuring the waste is neutralized or treated appropriately before disposal to minimize the risk of chemical exposure and environmental impact.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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![5-{4-[2-(5-Ethyl-1-oxido-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione — Hubei Yangxin Pharmaceutical Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cded3957537e5c8069af88/67cded3957537e5c8069af88-logo.webp){kind=logo}
![5-{4-[2-(5-Ethyl-1-oxido-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione — Cangzhou Narui Chemical Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cf2e8285715160a50de167/67cf2e8285715160a50de167-logo.webp){kind=logo}
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