Olmesartan | CAS No. 144689-24-7

Olmesartan

Basic Information

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CAS Number

144689-24-7

Molecular Formula

C24H26N6O3

Molecular Weight

446.51 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

186-188°C

Boiling Point

738.3°C at 760 mmHg

Density

1.33

Flash Point

400.3°C

Refractive Index

1.671

SMILES

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CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)C(C)(C)O

InChI

InChI=1S/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)

InChIKey

VTRAEEWXHOVJFV-UHFFFAOYSA-N

LogP

3.6566000000000023

Topological Polar Surface Area

129.80999999999997 Å²

Hydrogen Bond Donor/Acceptor

3 / 9

Complexity

656

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

NSC-759810
Q421156
BDBM50241364
Z1541758605
BCP12007
4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-carboxylic acid
Olmesartan [USAN:INN:BAN]
VTRAEEWXHOVJFV-UHFFFAOYSA-N
DE-092
HSDB 8214
CS 088
s5581
AKOS024458255
AS-10242
4-(1-hydroxy-1-methylethyl) -2-propyl-1-{4-[2-(tetrazole-5-yl)phenyl]phenyl}methylimidazole-5-carboxylic acid
4-(hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylic acid
L001097
Benicar;Olmetec
4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid
1H-IMidazole-5-carboxylicacid,4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-
4-(hydroxy-1-methylethyl)-2-propyl-1-{[2''-(1H-tetrazol-5-yl)-1,1''-biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid
D05246
omesartan
144689-24-7
4-(1-hydroxy-1-methylethyl) -2-propyl-1-{4-[2-(tetrazole -5-yl)phenyl]phenyl}methylimidazole-5-carboxylic acid
EC 646-413-5
4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylic acid
MLS000759446
Pharmakon1600-01505206
AC-9385
4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid

MDL Number

MFCD00914967

Customs Code

2921590090

FAQ

What is Olmesartan (CAS: 144689-24-7)?

Olmesartan is an angiotensin II receptor blocker (ARB) used primarily in the treatment of hypertension. Its chemical formula is C16H19N3O5S, and it is a white to off-white crystalline powder. It is known for its high selectivity for the AT1 receptor and is commonly used in pharmaceutical formulations.

What are the main uses of Olmesartan (CAS: 144689-24-7)?

Olmesartan is mainly used as an antihypertensive medication to lower blood pressure. It is also used in combination with other drugs for the management of hypertension. Its applications include cardiovascular disease prevention, and it is a key component in medications like Olmesartan Medoxomil.

Is Olmesartan (CAS: 144689-24-7) safe?

Olmesartan is generally considered safe when used as directed. However, it should be handled with care, and individuals with renal impairment or those on other medications should consult a healthcare provider. Safety standards ensure its proper use in pharmaceutical products.

How should Olmesartan (CAS: 144689-24-7) be stored?

Olmesartan should be stored in a cool, dry place away from moisture and light. It is typically kept in a sealed container at a temperature between 15°C to 30°C. Proper storage ensures its stability and effectiveness over time.