Thiazolidine hydrochloride

Basic Information

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CAS Number

14446-47-0

Molecular Formula

C3H8ClNS

Molecular Weight

125.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

SMILES

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C1CSCN1.Cl

InChI

InChI=1S/C3H7NS.ClH/c1-2-5-3-4-1;/h4H,1-3H2;1H

InChIKey

MPGQQQKGAXDBDN-UHFFFAOYSA-N

LogP

0.7021

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

30.1

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

Thiazolidine, hydrochloride
L-Proline, 2-(2-propenyl)- (9CI)
Thiazolidine, hydrochloride (1:1)
Thiazolidine hcl
THIAZOLIDINE, HCL (1:1)
thiazolidine hydrochloride
thiazolidinehydrochloride
Thiazolidine HCl (1:1)
1,3-thiazolidine hydrochloride
MPGQQQKGAXDBDN-UHFFFAOYSA-N
AK340267
CS-M1684
AKOS027338246
DB-361743
GS-5898
1,3-thiazolidine;hydrochloride
MFCD20483376
SCHEMBL4953104
Thiazolidine, HCl (1:1)
14446-47-0
A908653
H10192

MDL Number

MFCD20483376

FAQ

What are the physical and chemical properties of Thiazolidine hydrochloride (CAS: 14446-47-0)?

Thiazolidine hydrochloride is a crystalline solid with a molecular weight of approximately 189.66 g/mol. It has a solubility of 10 g/L in water and is slightly soluble in ethanol. It is chemically stable but can react with strong bases to form the thiazolidine anion. Commonly, it is used in organic synthesis as a reagent.

How is Thiazolidine hydrochloride (CAS: 14446-47-0) typically synthesized?

Thiazolidine hydrochloride is typically synthesized by reacting thiazolidine with hydrochloric acid. The reaction is carried out in an aqueous medium and the product is isolated by recrystallization from water. The yield is usually around 90%, and the reaction is selective and proceeds efficiently.

What industries use Thiazolidine hydrochloride (CAS: 14446-47-0)?

Thiazolidine hydrochloride is used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also has applications in the polymer industry for functionalizing polymers and in the sensor industry as a probe for detecting specific chemical compounds. Additionally, it can be used in the semiconductor industry as a reagent.

What precautions should be taken when handling Thiazolidine hydrochloride (CAS: 14446-47-0)?

When handling Thiazolidine hydrochloride, it is important to wear protective equipment such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood. In case of spillage, use appropriate spill cleanup procedures as outlined in the Safety Data Sheet (SDS). Thiazolidine hydrochloride is not particularly hazardous, but care should be taken to avoid exposure to strong bases.