1,3-Thiazol-5-ylmethyl [(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenyl-2-hexanyl]carbamate

Basic Information

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CAS Number

144164-11-4

Molecular Formula

C23H27N3O3S

Molecular Weight

425.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

656.1°C at 760 mmHg

Density

1.251

Flash Point

350.6°C

Refractive Index

1.619

SMILES

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C1=CC=C(C=C1)CC(CC(C(CC2=CC=CC=C2)NC(=O)OCC3=CN=CS3)O)N

InChI

InChI=1S/C23H27N3O3S/c24-19(11-17-7-3-1-4-8-17)13-22(27)21(12-18-9-5-2-6-10-18)26-23(28)29-15-20-14-25-16-30-20/h1-10,14,16,19,21-22,27H,11-13,15,24H2,(H,26,28)/t19-,21-,22-/m0/s1

InChIKey

HBPTXDXGWDVDON-BVSLBCMMSA-N

LogP

3.301600000000002

Topological Polar Surface Area

97.47 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

498

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

A808185
(2S,3S,5S)-5-amino-2-(N-((5-thiazolyl) methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
BCP22733
(2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1,6diphenyl-3-hydroxyhexane
(2S,3S,5S)-5-AMINO-2-(N-((5-THIAZOLYL)-METHOXYCARBONYL)AMINO)-1,6-DIPHENYL-3-HYDROXYHEXANE
1,3-thiazol-5-ylmethyl (1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentylcarbamate
(2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)- 1,6-diphenyl-3-hydroxyhexane
HBPTXDXGWDVDON-BVSLBCMMSA-N
(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1.6-diphenyl-3-hydroxyhexane
(1,3-Thiazol-5-yl)methyl [(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl]carbamate
1,3-THIAZOL-5-YLMETHYL N-[(2S,3S,5S)-5-AMINO-3-HYDROXY-1,6-DIPHENYLHEXAN-2-YL]CARBAMATE
(2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino )-1,6-diphenyl-3- hydroxyhexane
Thiazol-5-ylmethyl((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate
Carbamic acid, N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester
2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane
144164-11-4
1,3-thiazol-5-ylmethyl(1s,2s,4s)-4-amino-1-benzyl-2-hydroxy-5-phenylpentylcarbamate
(2S,3S,5S )-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
DS-18504
AKOS015896455
SCHEMBL893198
DTXSID10455244
J-007926
Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate
C23H27N3O3S
CS-0149754
J-524904
MFCD07367634
(2 S,3S,5S)-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
(2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
AC-8900

MDL Number

MFCD07367634

FAQ

What regulatory guidelines apply to 1,3-Thiazol-5-ylmethyl [(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenyl-2-hexanyl]carbamate (CAS: 144164-11-4)?

This compound is subject to various regulatory guidelines including REACH in the EU for registration, evaluation, authorization, and restriction of chemical substances. It should comply with GHS (Globally Harmonized System of Classification and Labelling of Chemicals) for classification and labeling. FDA may regulate it as a pharmaceutical ingredient, and EPA may oversee its environmental impact and disposal under the Toxic Substances Control Act (TSCA).

Are there alternatives to 1,3-Thiazol-5-ylmethyl [(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenyl-2-hexanyl]carbamate (CAS: 144164-11-4) in synthesis?

Synthetic alternatives include using isomers or analogs such as 1,3-thiazol-5-ylmethyl [(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenyl-2-hexan-1-yl]carbamate. Common alternative reagents might include other amino acids or thiazole derivatives depending on the specific synthesis process requirements.

What is the market or research trend for 1,3-Thiazol-5-ylmethyl [(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenyl-2-hexanyl]carbamate (CAS: 144164-11-4)?

Recent market trends indicate increasing research and development interest in this compound, particularly in pharmaceutical applications due to its potential as a drug candidate. Price trends reflect growing demand, but research efforts focus on optimizing synthesis and exploring new therapeutic potentials.

How should waste containing 1,3-Thiazol-5-ylmethyl [(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenyl-2-hexanyl]carbamate (CAS: 144164-11-4) be handled?

Waste containing this compound should be collected in appropriate containers and disposed of through professional waste disposal services. Environmental protection precautions include neutralizing the waste to minimize environmental impact before disposal. Incineration or chemical destruction methods may also be considered, ensuring compliance with local regulations and safety standards.