[(2R)-1-Methyl-2-pyrrolidinyl](diphenyl)methanol

Basic Information

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CAS Number

144119-12-0

Molecular Formula

C18H21NO

Molecular Weight

267.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

70.0 to 73.0 deg-C

Boiling Point

406.8 °C at 760 mmHg

Density

1.116

Flash Point

196.8 °C

Refractive Index

-55 ° (C=1, CHCl3)

Specific Rotation

-52° (c=1, CHCl3)

SMILES

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CN1CCCC1C(C2=CC=CC=C2)(C3=CC=CC=C3)O

InChI

InChI=1S/C18H21NO/c1-19-14-8-13-17(19)18(20,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17,20H,8,13-14H2,1H3/t17-/m1/s1

InChIKey

XIJAGFLYYNXCAB-QGZVFWFLSA-N

LogP

3.016700000000002

Topological Polar Surface Area

23.47 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

287

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

CS-W012413
AKOS007930843
(R)-1-Methyl-2-(diphenylhydroxymethyl)pyrrolidine
1,1-diphenyl-n-methyl-d-prolinol
(R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine
[(2R)-1-methylpyrrolidin-2-yl]-diphenylmethanol
(R)-alpha,alpha-Diphenyl-N-methyl-2-pyrrolidinemethanol
(2R)-N-Methyl-alpha,alpha-diphenyl-2-pyrrolidinemethanol
1,1-diphenyl-(n-methyl-pyrroline-2-yl)-methanol
(r)-n-methyl-alpha,alpha-diphenyl-2-pyrrolidinemethanol
[(2R)-1-methylpyrrolidin-2-yl]diphenylmethanol
alpha,alpha-Diphenyl-N-methyl-D-prolinol
H0784
(r)-n-methyl-a,a-diphenyl-2-pyrrolidine methanol
alpha,alpha-Diphenyl-N-methyl-D-prolinol, >=99% (sum of enantiomers, GC)
AS-69024
d-diphenylmethylprolinol
144119-12-0
(r)-alpha,alpha-diphenylmethylprolinol
(R)-(1-Methylpyrrolidin-2-yl)diphenylmethanol
MFCD00145217
(R)-N-Methyl-alpha,alpha-diphenyl-2-pyrrolidine methanol
(2r)-1-methyl-alpha,alpha-diphenyl-2-pyrrolidinemethanol
(R)-(-)-Diphenyl(1-methylpyrrolidin-2-yl)methanol
(r)-a,a-n-methyl diphenyl-2-pyrrolidine methanol
Q-102755
TD8074
((r)-1-methylpyrrolidin-2-yl)diphenylmethanol
(r)-a,a-diphenylmethylprolinol
SCHEMBL7922116
2-Pyrrolidinemethanol, 1-methyl-alpha,alpha-diphenyl-, (2R)-

MDL Number

MFCD00145217

Customs Code

2933990090

FAQ

What is (2R)-1-Methyl-2-pyrrolidinyl(diphenyl)methanol (CAS: 144119-12-0)?

(2R)-1-Methyl-2-pyrrolidinyl(diphenyl)methanol, also known as (2R)-1-methyl-2-(diphenylmethyl)pyrrolidine, is a colorless to light yellow liquid with a distinctive odor. It has a molecular weight of approximately 328.34 g/mol and a boiling point of around 230°C. It is used in pharmaceuticals as an intermediate in the synthesis of drugs and in research due to its unique chemical structure.

What are the main uses of (2R)-1-Methyl-2-pyrrolidinyl(diphenyl)methanol (CAS: 144119-12-0)?

(2R)-1-Methyl-2-pyrrolidinyl(diphenyl)methanol is primarily used as an intermediate in the pharmaceutical industry. It plays a crucial role in the synthesis of various drugs and is also utilized in research for its unique chemical properties. Due to its structural complexity, it can be employed in developing new medications and therapeutic agents.

Is (2R)-1-Methyl-2-pyrrolidinyl(diphenyl)methanol (CAS: 144119-12-0) safe?

(2R)-1-Methyl-2-pyrrolidinyl(diphenyl)methanol is generally safe when handled with appropriate precautions. However, it should be used in a well-ventilated area and with proper protective equipment, such as gloves and goggles, to minimize skin and eye contact. Avoid inhaling the vapors and ensure good laboratory practices are followed to reduce the risk of exposure.

How should (2R)-1-Methyl-2-pyrrolidinyl(diphenyl)methanol (CAS: 144119-12-0) be stored?

(2R)-1-Methyl-2-pyrrolidinyl(diphenyl)methanol should be stored in a cool, dry place away from direct sunlight and heat sources. It is recommended to keep it in a sealed container to prevent evaporation and contamination. Store it at temperatures between 15-25°C and avoid freezing. Proper labeling and documentation of the storage conditions are essential for safe handling.