A 419259 trihydrochloride

Basic Information

View in Editor

CAS Number

1435934-25-0

Molecular Formula

C29H37Cl3N6O

Molecular Weight

592.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

CN1CCN(CC1)C2CCC(CC2)N3C=C(C4=C(N=CN=C43)N)C5=CC=C(C=C5)OC6=CC=CC=C6.Cl.Cl.Cl

InChI

InChI=1S/C29H34N6O.3ClH/c1-33-15-17-34(18-16-33)22-9-11-23(12-10-22)35-19-26(27-28(30)31-20-32-29(27)35)21-7-13-25(14-8-21)36-24-5-3-2-4-6-24;;;/h2-8,13-14,19-20,22-23H,9-12,15-18H2,1H3,(H2,30,31,32);3*1H/t22-,23-;;;

InChIKey

ALRMEQIQFCUAMR-KOONDFAVSA-N

LogP

6.469300000000007

Topological Polar Surface Area

72.44 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

679

Synonyms & References

English

7-[trans-4-(4-Methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl )-7H-pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride
A 419259 trihydrochloride
A-419259 trihydrochloride
RK 20449 trihydrochloride
RK-20449 trihydrochloride
A 419259 (trihydrochloride)
CultureSure® A419259 Trihydrochloride
BCP25095
7-((1r,4r)-4-(4-methylpiperazin-1-yl)cyclohexyl)-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride
A909639
CHEMBL5305336
F84980
7-[trans-4-(4-Methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride; A-419259 Trihydrochloride
a-419259 trihydrochloride
HY-15764A
7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine;trihydrochloride
A-419259 (hydrochloride)
RK-20449
7-[cis-4-(4-Methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CS-1705
GLXC-02002
A913772
J-007843
DA-70415
A 419259 (trihydrochloride)?
MS-30537
PD118374
RK 20448-Trihydrochloride
5-(4-PHENOXYPHENYL)-7-[(1R,4R)-4-(4-METHYLPIPERAZIN-1-YL)CYCLOHEXYL]PYRROLO[2,3-D]PYRIMIDIN-4-AMINE TRIHYDROCHLORIDE
EX-A1443
5-(4-phenoxyphenyl)-7-[(1r,4r)-4-(4-methylpiperazin-1-yl)cyclohexyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride

MDL Number

MFCD19690922

FAQ

What are the physical and chemical properties of A 419259 trihydrochloride (CAS: 1435934-25-0)?

A 419259 trihydrochloride is a crystalline solid with a molecular weight of approximately 600 g/mol. It has a high solubility in water and moderate solubility in organic solvents. The compound is relatively stable under normal conditions but can react with bases to form the free base. It is typically used in pharmaceutical applications and may exhibit pH-dependent solubility characteristics.

How is A 419259 trihydrochloride (CAS: 1435934-25-0) typically synthesized?

A 419259 trihydrochloride is synthesized by reacting the parent compound with hydrochloric acid. Commonly, this involves dissolving the parent compound in a suitable solvent, followed by the addition of hydrochloric acid. The reaction is usually carried out under mild conditions with good yield and selectivity. The reaction mixture is then neutralized and the trihydrochloride is isolated by crystallization.

What industries use A 419259 trihydrochloride (CAS: 1435934-25-0)?

A 419259 trihydrochloride is primarily used in the pharmaceutical industry for the development of new drugs. It is also utilized in the polymer industry for the synthesis of certain polymeric materials. Additionally, it finds applications in the semiconductor industry for use in sensor fabrication and as a dopant in electronic devices.

What precautions should be taken when handling A 419259 trihydrochloride (CAS: 1435934-25-0)?

When handling A 419259 trihydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be stored in a well-ventilated area and handled in a fume hood to minimize inhalation risk. In case of spillage, it should be cleaned up using appropriate absorbent materials and the area should be thoroughly rinsed with water. Personnel should consult the Safety Data Sheet (SDS) for detailed information on handling and emergency procedures.