5-(Dimethylamino)naphthalene-1-sulfonamide

Basic Information

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CAS Number

1431-39-6

Molecular Formula

C12H14N2O2S

Molecular Weight

250.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

218.0 to 222.0 deg-C

Boiling Point

435.4°Cat760mmHg

Flash Point

217.1°C

Refractive Index

1.5950 (estimate)

SMILES

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CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)N

InChI

InChI=1S/C12H14N2O2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3,(H2,13,15,16)

InChIKey

TYNBFJJKZPTRKS-UHFFFAOYSA-N

LogP

1.5532000000000001

Topological Polar Surface Area

63.4 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

361

Synonyms & References

English

FT-0624411
UNII-ZUZ5S5875E
5-DIMETHYLAMINO-1-NAPHTHALENESULFONAMIDE
MFCD00004000
AKOS003242506
Dansylamide
BP-12687
CHEMBL119489
5-Dimethylamino-1-naphthalene sulfonamide
Q4154890
InChI=1/C12H14N2O2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3,(H2,13,15,16)
D5405
NS00024655
1-Naphthalenesulfonamide, 5-(dimethylamino)-
5-(Dimethylamino)naphthalene-1-sulphonamide
HY-118562
CS-0067480
T70280
5-Dimethylaminonaphthalene-1-sulfonamide
5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONAMIDE
TYNBFJJKZPTRKS-UHFFFAOYSA-
5-Dimethylamino-1-naphthylsulfonamid
Dansyl amide
5-(dimethylamino)naphthalene-1-sulfonamide
D1507
5-dimethylamino-1-naphthalenesulphonamide
EN300-372001
Dansyl-1-sulfonamide
1-Dimethylaminonaphthalene-5-sulfonamide
Dansylamide [for Albumin binding assay]
Oprea1_628153

MDL Number

MFCD00004000

Customs Code

2935009090

FAQ

What are the physical and chemical properties of 5-(Dimethylamino)naphthalene-1-sulfonamide (CAS: 1431-39-6)?

5-(Dimethylamino)naphthalene-1-sulfonamide (CAS: 1431-39-6) is a crystalline compound with a molecular weight of approximately 252.26 g/mol. It has poor water solubility but good solubility in organic solvents like ethanol and acetone. This compound shows basic properties due to its amine group and is known for its stability under normal conditions but can react with strong acids and bases. It is often used in biological and pharmaceutical applications due to its chemical reactivity.

How is 5-(Dimethylamino)naphthalene-1-sulfonamide (CAS: 1431-39-6) typically synthesized?

5-(Dimethylamino)naphthalene-1-sulfonamide is typically synthesized through the reaction of naphthol with dimethylamine in the presence of a sulfonating agent like sulfur trioxide. Common methods include the use of metaphosphoric acid or oleum as the sulfonating agent. The reaction involves the sulfonation step followed by the coupling with the amine. The yield is generally good, and the product can be purified by recrystallization.

What industries use 5-(Dimethylamino)naphthalene-1-sulfonamide (CAS: 1431-39-6)?

5-(Dimethylamino)naphthalene-1-sulfonamide (CAS: 1431-39-6) is primarily used in pharmaceuticals for dyeing and as a chromogen in biological assays. It is also utilized in the polymer industry as a colorant and in the semiconductor industry as a dopant. Additionally, it has applications in sensor technology due to its optical properties.

What precautions should be taken when handling 5-(Dimethylamino)naphthalene-1-sulfonamide (CAS: 1431-39-6)?

When handling 5-(Dimethylamino)naphthalene-1-sulfonamide (CAS: 1431-39-6), it is important to wear appropriate personal protective equipment such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from heat and direct sunlight. In case of a spill, it should be carefully cleaned up with absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.