Compound Q&A
How is 5-(Dimethylamino)naphthalene-1-sulfonamide (CAS: 1431-39-6) typically synthesized?
Answer
5-(Dimethylamino)naphthalene-1-sulfonamide is typically synthesized through the reaction of naphthol with dimethylamine in the presence of a sulfonating agent like sulfur trioxide. Common methods include the use of metaphosphoric acid or oleum as the sulfonating agent. The reaction involves the sulfonation step followed by the coupling with the amine. The yield is generally good, and the product can be purified by recrystallization.
About
CAS No
1431-39-6
English Name
5-(Dimethylamino)naphthalene-1-sulfonamide
Molecular Formula
C12H14N2O2S
Molecular Weight
250.32 g/mol
SMILES
CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)N
InChIKey
TYNBFJJKZPTRKS-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04
