4-Chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine

Basic Information

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CAS Number

142994-19-2

Molecular Formula

C24H20ClNO4

Molecular Weight

421.88 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

194 ºC

Boiling Point

640.9°Cat760mmHg

Density

1.1529 (rough estimate)

Flash Point

341.4°C

Refractive Index

1.6290 (estimate)

Specific Rotation

30 º (c=1,DMF)

SMILES

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C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CC=C(C=C4)Cl)C(=O)O

InChI

InChI=1S/C24H20ClNO4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/t22-/m1/s1

InChIKey

CQPNKLNINBUUOM-JOCHJYFZSA-N

LogP

4.874400000000004

Topological Polar Surface Area

75.63000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

584

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

CHEMBL1365383
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-chlorophenyl)propanoic acid
(2R)-3-(4-chlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate;Fmoc-D-Phe(4-Cl)-OH
142994-19-2
CQPNKLNINBUUOM-JOCHJYFZSA-N
Fmoc-D-Phe(4-Cl)-OH, >=98.0% (HPLC)
Fmoc-D-Phe(4-Cl)-OH
DTXSID70583794
N-FLUORENEMETHOXYCARBONYL-D-4-CHLORO PHENYLALANINE
CS-W011646
Fmoc-(D)Phe(4-Cl)-OH
FMOC-4-CHLORO-D-PHE-OH
J-300392
4-CHLORO-N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-D-PHENYLALANINE
SCHEMBL119558
Fmoc-D-4-Chlorophenylalanine
(R)-3-(4-Chloro-phenyl)-2-(Fmoc-amino)-propionic acid;Fmoc-4-chloro-D-Phe-OH
D-PHENYLALANINE, 4-CHLORO-N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-
HMS2198P04
HY-W010930
4-Chloro-N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-D-phenylalanine
(R)-2-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-3-(4-CHLOROPHENYL)PROPANOIC ACID
AKOS015837387
AM82753
A807998
N-alpha-(9-Fluorenylmethyloxycarbonyl)-D-4-chloro-phenylalanine (Fmoc-D-Phe(4-Cl)-OH)
Fmoc-D-4-Chlorophe
EN300-3408766
(2R)-3-(4-chlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
Fmoc-L-phe(4-Cl)-OH
4-Chloro-N-Fmoc-D-phenylalanine

MDL Number

MFCD00077066

FAQ

What is 4-Chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine (CAS: 142994-19-2)?

4-Chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine, also known as chloromethylfluorenyl-D-phenylalanine, is a synthetic organic compound with the CAS number 142994-19-2. It is a protected amino acid derivative with potential applications in pharmaceuticals and research.

What are the main uses of 4-Chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine (CAS: 142994-19-2)?

4-Chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine is primarily used in the development of pharmaceuticals and as a research tool. It serves as a protected amino acid in organic synthesis and drug design, facilitating the construction of complex molecules.

Is 4-Chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine (CAS: 142994-19-2) safe?

4-Chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine is generally considered safe for laboratory use with appropriate precautions. Users should handle the compound in a fume hood, wear gloves and protective eyewear, and avoid skin contact and inhalation. Storage should be in a cool, dry place away from direct sunlight.

How should 4-Chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine (CAS: 142994-19-2) be stored?

4-Chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine should be stored in a tightly sealed container at a temperature below 25°C, away from direct sunlight and heat sources. Maintain a dry environment, and avoid exposure to moisture and air to prevent degradation.