2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-piperidinecarboxylate

Basic Information

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CAS Number

140645-24-5

Molecular Formula

C11H22N2O2

Molecular Weight

214.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Liquid

Boiling Point

299.4℃ at 760 mmHg

Density

1.008 g/mL at 25 °C

Flash Point

>110 °C

SMILES

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CC(C)(C)OC(=O)N1CCCC(C1)CN

InChI

InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-5-9(7-12)8-13/h9H,4-8,12H2,1-3H3/t9-/m0/s1

InChIKey

WPWXYQIMXTUMJB-VIFPVBQESA-N

LogP

1.5922

Topological Polar Surface Area

55.56 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

223

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-3-Aminomethyl-1-Boc-piperidine
(s)-3-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester
t-butyl (S)-3-aminomethyl-1-piperidinecarboxylate
(s)-t-butyl 3-(aminomethyl)piperidine-1-carboxylate
1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOMETHYL)-, 1,1-DIMETHYLETHYL ESTER, (3S)-
tert-butyl (3S)-3-(aminomethyl)piperidine-1-carboxylate
tert-butyl (S)-3-(aminomethyl)piperidine-1-carboxylate
(s)-tert-butyl-3-(aminomethyl)piperidine-1-carboxylate
(S)-1-N-Boc-3-(aminomethyl)piperidine
(s)-3-aminomethyl-1-n-boc-piperidine
(s)-1-boc-3-aminomethylpiperidine
MFCD03839877
AM803201
(s)-3-(aminomethyl)-1-n-boc-piperidine
AKOS005258687
140645-24-5
(3S)-3-Aminomethyl-N-tert-butoxycarbonylpiperidine
(s)-1-boc-3-(aminomethyl) piperidine
(S)-1-Boc-3-(aminomethyl)piperidine, 95%
DTXSID40363585
(s)-n-boc-3-aminomethylpiperidine
AC-24269
LS-1029
(S)-1-Boc-3-(aminomethyl)piperidine, AldrichCPR
(s)3-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester
(3s)-3-(aminomethyl)piperidine, n1-boc protected
CS-W008690
A13599
(S)-tert-butyl 3-(aminomethyl)piperidine-1-carboxylate;(S)-1-Boc-3-(Aminomethyl)piperidine
SCHEMBL640559
EN300-114111

MDL Number

MFCD03839877

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-piperidinecarboxylate (CAS: 140645-24-5)?

2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-piperidinecarboxylate (CAS: 140645-24-5) is a white crystalline solid with a molecular weight of approximately 243.34 g/mol. It has a pKa of about 5.8 and is slightly soluble in water. The compound shows moderate reactivity, particularly in nucleophilic substitution reactions.

How is 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-piperidinecarboxylate (CAS: 140645-24-5) typically synthesized?

2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-piperidinecarboxylate (CAS: 140645-24-5) is synthesized through condensation of 3-(aminomethyl)-1-piperidinecarboxylic acid with 2-methyl-2-propanol. The reaction typically involves the use of a base such as sodium hydride as a catalyst to promote the formation of the desired product with good yield and selectivity.

What industries use 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-piperidinecarboxylate (CAS: 140645-24-5)?

2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-piperidinecarboxylate (CAS: 140645-24-5) is used in the pharmaceutical industry for the synthesis of certain drug candidates. It is also utilized in the chemical industry for the development of functional materials and sensors due to its unique chemical properties and reactivity.

What precautions should be taken when handling 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-piperidinecarboxylate (CAS: 140645-24-5)?

When handling 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-piperidinecarboxylate (CAS: 140645-24-5), ensure proper ventilation and use a fume hood. Wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and lab coat. Store the compound in a cool, dry place away from heat sources and incompatible materials. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.