2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride (1:1) (non-preferred name) | CAS No. 14046-64-1

2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride (1:1) (non-preferred name)

Basic Information

CAS Number

14046-64-1

Molecular Formula

C10H16ClN3O5

Molecular Weight

293.71 g/mol

AD

Basic Physical Properties

Solubility

H2O: 10 mg/mL

C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O.Cl

InChI

InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H

InChIKey

ULFCBIUXQQYDEI-UHFFFAOYSA-N

LogP

-1.3344000000000003

Topological Polar Surface Area

148.07 Ų

Hydrogen Bond Donor/Acceptor

8 / 8

Complexity

278

Synonyms & References

English

  • Benserazide hydrochloride; (2RS)-2-Amino-3-hydroxy-2'-(2,3,4-trihydroxybenzyl)propanohydrazide hydrochloride
  • NS00076155
  • Benserazide hydrochloride - Bio-X
  • Benserazide (as hydrochloride)
  • 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazidehydrochloride
  • NSC 755907
  • BB166155
  • Tox21_110573
  • UNII-B66E5RK36Q
  • B 7283
  • Benserazide hydrochloride, European Pharmacopoeia (EP) Reference Standard
  • DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
  • MFCD00078571
  • HMS1920G05
  • B4108
  • 2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)-propanehydrazide hydrochloride;Benserazide HCl
  • Benserazide (hydrochloride)
  • FT-0659734
  • 2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide hydrochloride
  • CHEMBL1255778
  • Opera_ID_1594
  • AKOS007930267
  • DL-Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide hydrochloride
  • SCHEMBL364720
  • AC-6825
  • NCGC00093698-04
  • Ro 4-4602/001
  • (S)-2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride
  • Benserazide hydrochloride, >=98% (TLC), solid
  • Benserazide for peak identification, European Pharmacopoeia (EP) Reference Standard
  • NCGC00016709-01

Customs Code

2928000090

FAQ

What are the physical and chemical properties of 2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride (CAS: 14046-64-1)?

2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride (CAS: 14046-64-1) has a crystalline form and a molecular weight of approximately 373.25 g/mol. It is sparingly soluble in water and alcohol. The compound exhibits moderate reactivity, particularly in basic conditions, and is known for its stability under neutral and acidic conditions.

How is 2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride (CAS: 14046-64-1) typically synthesized?

2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride (CAS: 14046-64-1) is typically synthesized via the amidation of 2-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide with 2-aminoacetic acid hydrochloride. The reaction is catalyzed by an appropriate base and proceeds with good yield and selectivity. Proper handling of reagents and solvents is essential to ensure safety and high-quality product.

What industries use 2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride (CAS: 14046-64-1)?

2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride (CAS: 14046-64-1) is used in various industries, including pharmaceuticals, where it serves as a precursor for drug synthesis. It also finds applications in the production of polymers, sensors, and semiconductors due to its unique chemical properties and reactivity.

What precautions should be taken when handling 2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride (CAS: 14046-64-1)?

When handling 2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride (CAS: 14046-64-1), it is important to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. Handle the compound in a fume hood to avoid inhalation. Spills should be neutralized with an appropriate acid-base buffer and then cleaned up using standard laboratory procedures. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.

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