Vancomycin | CAS No. 1404-90-6

Vancomycin

Basic Information

View in Editor

CAS Number

1404-90-6

Molecular Formula

C66H75Cl2N9O24

Molecular Weight

1449.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

CNC(CC(C)C)C(=O)NC1C(O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)C(O)C5NC(=O)C(NC(=O)C4NC(=O)C(CC(N)=O)NC1=O)c1ccc(O)c(c1)-c1c(O)cc(O)cc1C(NC5=O)C(O)=O)c3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1)c(Cl)c2

InChI

InChI=1S/C66H75Cl2N9O24/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95)

InChIKey

MYPYJXKWCTUITO-UHFFFAOYSA-N

LogP

0.10620000000000951

Topological Polar Surface Area

530.4900000000001 Å²

Hydrogen Bond Donor/Acceptor

21 / 33

Complexity

2960

Synonyms & References

English

Vancomycin
Vancomycin HCl
22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine,vancomycin deriv.
Vancocin
Vancoled
Vancomycinum
Vancomycine
Vancomicina
Vancomycinum [INN-Latin]
Vancomycine [INN-French]
VANCOR
Vancomicina [INN-Spanish]
6Q205EH1VU
Vancocin HCL
Vancomycin (USP)
vancomicin
vanomycin
Vancomycin [USP:INN:BAN]
Vancomycin [USAN:INN:BAN]
Vancomycin hydrochloride from Streptomyces orientalis
C66H75Cl2N9O24
Viomycin derivative
[(2S,3R,4S,5S,6R)-3-[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6

MDL Number

MFCD05664587

Customs Code

3004209090

FAQ

What is Vancomycin (CAS: 1404-90-6)?

Vancomycin (CAS: 1404-90-6) is a glycopeptide antibiotic used to treat severe bacterial infections. It has the chemical formula C19H32Cl2N6O5S2 and is known for its effectiveness against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Vancomycin works by inhibiting bacterial cell wall synthesis, making it a critical component in pharmaceuticals for resistant infections.

What are the main uses of Vancomycin (CAS: 1404-90-6)?

Vancomycin (CAS: 1404-90-6) is primarily used in healthcare to combat severe infections such as endocarditis, osteomyelitis, and bloodstream infections caused by gram-positive bacteria. It is also employed in veterinary medicine and research for antimicrobial studies. As a last-line antibiotic, Vancomycin plays a vital role in treating drug-resistant bacterial strains, including MRSA, in clinical settings.

Is Vancomycin (CAS: 1404-90-6) safe?

Vancomycin (CAS: 1404-90-6) is generally safe when used as prescribed, but it requires careful handling due to potential side effects like nephrotoxicity, ototoxicity, and allergic reactions. Safety guidelines emphasize monitoring kidney function and avoiding excessive doses. Proper protective measures, such as gloves and eye protection, are necessary during handling to ensure compliance with safety standards and minimize risks.

How should Vancomycin (CAS: 1404-90-6) be stored?

Vancomycin (CAS: 1404-90-6) should be stored in a cool, dry place at 20-25°C (68-77°F), away from light and moisture. It must be kept in its original container, tightly sealed, and protected from contamination. Storage conditions should maintain stability and potency, with adherence to expiration dates to ensure effectiveness and safety for medical use.