2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one | CAS No. 1367369-78-5

2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one

Basic Information

CAS Number

1367369-78-5

Molecular Formula

C12H15N5O3

Molecular Weight

277.28 g/mol

AD

Basic Physical Properties

OC[C@@H]1[C@@H](O)C[C@H](C1=C)n1cnc2c1nc(N)[nH]c2=O

InChI

InChI=1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7+,8-/m0/s1

InChIKey

QDGZDCVAUDNJFG-RNJXMRFFSA-N

LogP

-0.8278000000000001

Topological Polar Surface Area

130.04999999999998 Ų

Hydrogen Bond Donor/Acceptor

5 / 8

Complexity

480

Synonyms & References

English

  • 1’-epi-Entecavir
  • LNS2U38C9S
  • 2-Amino-1,9-dihydro-9-((1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-6H-purin-6-one
  • Entecavir 1-epimer
  • Entecavir 1-epimer [USP]
  • 1R3R4S-entecavir (impurity)
  • 9-((1R,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)guanine
  • 2-Amino-9-((1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one
  • 2-Amino-9-((1R,3R,4S)-4-h
  • 2-amino-9-((1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one

MDL Number

MFCD16659047

FAQ

What regulatory guidelines apply to 2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one (CAS: 1367369-78-5)?

2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one (CAS: 1367369-78-5) falls under various regulatory frameworks. It should comply with GHS classification for hazardous materials. For synthesis and import/export, REACH regulations in the EU apply, requiring notification and registration of substances. In the U.S., FDA and EPA regulations might be relevant for pharmaceutical and environmental concerns, respectively.

Are there alternatives to 2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one (CAS: 1367369-78-5) in synthesis?

While 2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one (CAS: 1367369-78-5) is a unique molecule, it can be synthesized using analogs like 9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one or by substituting key functional groups. Common alternatives include using different reagents or adjusting reaction conditions to achieve similar structural features.

What is the market or research trend for 2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one (CAS: 1367369-78-5)?

The market for 2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one (CAS: 1367369-78-5) is driven by its potential applications in pharmaceuticals and biochemistry. Research trends focus on its pharmacological effects and structural modifications. Market analysis suggests increasing demand in specialized chemical markets, with ongoing studies exploring its therapeutic potentials.

How should waste containing 2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one (CAS: 1367369-78-5) be handled?

Waste containing 2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one (CAS: 1367369-78-5) should be collected in appropriate containers and disposed of according to local hazardous waste regulations. For safe disposal, incineration or professional waste disposal services are recommended. Ensure all environmental protection precautions are followed to minimize environmental impact.

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