Dermaseptin | CAS No. 136212-91-4

Dermaseptin

Basic Information

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CAS Number

136212-91-4

Molecular Formula

C152H257N43O44S2

Molecular Weight

3455.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CCC(C)C(C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(C(C)O)C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C(C(C)O)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(C)NC(=O)C(CC1=CN=CN1)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C(C(C)O)NC(=O)C(CCCCN)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC(C)C)NC(=O)C(C)N

InChI

InChI=1S/C152H257N43O44S2/c1-27-77(12)118(147(233)190-110(70-196)146(232)178-98(44-46-111(158)201)131(217)163-68-115(205)192-120(87(22)198)149(235)181-101(152(238)239)45-47-112(159)202)193-151(237)122(89(24)200)195-145(231)109(63-117(207)208)185-129(215)84(19)169-126(212)81(16)168-125(211)80(15)167-113(203)66-164-132(218)102(56-72(2)3)183-128(214)83(18)170-127(213)82(17)172-134(220)94(40-30-34-50-153)174-114(204)67-162-124(210)79(14)171-140(226)108(62-91-65-160-71-166-91)189-143(229)105(59-75(8)9)184-130(216)85(20)173-135(221)99(48-54-240-25)179-148(234)119(86(21)197)191-116(206)69-165-133(219)103(57-73(4)5)186-137(223)96(42-32-36-52-155)175-136(222)95(41-31-35-51-154)176-141(227)106(60-76(10)11)187-138(224)100(49-55-241-26)180-150(236)121(88(23)199)194-139(225)97(43-33-37-53-156)177-144(230)107(61-90-64-161-93-39-29-28-38-92(90)93)188-142(228)104(58-74(6)7)182-123(209)78(13)157/h28-29,38-39,64-65,71-89,94-110,118-122,161,196-200H,27,30-37,40-63,66-70,153-157H2,1-26H3,(H2,158,201)(H2,159,202)(H,160,166)(H,162,210)(H,163,217)(H,164,218)(H,165,219)(H,167,203)(H,168,211)(H,169,212)(H,170,213)(H,171,226)(H,172,220)(H,173,221)(H,174,204)(H,175,222)(H,176,227)(H,177,230)(H,178,232)(H,179,234)(H,180,236)(H,181,235)(H,182,209)(H,183,214)(H,184,216)(H,185,215)(H,186,223)(H,187,224)(H,188,228)(H,189,229)(H,190,233)(H,191,206)(H,192,205)(H,193,237)(H,194,225)(H,195,231)(H,207,208)(H,238,239)/t77-,78-,79-,80-,81-,82-,83-,84-,85-,86+,87+,88+,89+,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,118-,119-,120-,121-,122-/m0/s1

InChIKey

YFHLIDBAPTWLGU-CTKMSOPVSA-N

LogP

-14.40870000000014

Topological Polar Surface Area

1396.7999999999995 Å²

Hydrogen Bond Donor/Acceptor

56 / 87

Complexity

7840

Synonyms & References

English

MFCD00146655
Dermaseptin DS 01
NH2-Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly-Thr-Gln-COOH
CHEMBL525200
Dermaseptin
Dermaseptin I
Dermaseptin from Phyllomedusa sauvagii
Dermaseptin (H-L-Ala-L-Leu-L-Trp-L-Lys-L-Thr-L-Met-L-Leu-L-Lys-L-Lys-L-Leu-Gly-L-Thr-L-Met-L-Ala-L-Leu-L-His-L-Ala-Gly-L-Lys-L-Ala-L-Ala-L-Leu-Gly-L-Ala-L-Ala-L-Ala-L-Asp-L-Thr-L-Ile-L-Ser-L-Gln-Gly-L-Thr-L-Gln-OH)
L-Glutamine, L-alanyl-L-leucyl-L-tryptophyl-L-lysyl-L-threonyl-L-methionyl-L-leucyl-L-lysyl-L-lysyl-L-leucylglycyl-L-threonyl-L-methionyl-L-alanyl-L-leucyl-L-histidyl-L-alanylglycyl-L-lysyl-L-alanyl-L-alanyl-L-leucylglycyl-L-alanyl-L-alanyl-L-alanyl-L-.alpha.-aspartyl-L-threonyl-L-isoleucyl-L-seryl-L-glutaminylglycyl-L-threonyl-
Dermaseptin S
dermaseptin S1
136033-70-0
Dermaseptin S3(1-16)
136212-91-4
Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys Lys-Leu-Gly-Thr-Met-Ala-Leu-His Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly Thr-Gln
ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
Dermaseptin s

MDL Number

MFCD00146655

FAQ

What regulatory guidelines apply to Dermaseptin (CAS: 136212-91-4)?

Dermaseptin (CAS: 136212-91-4) falls under several regulatory frameworks such as GHS for hazard communication, REACH for chemical registration in Europe, and FDA/EPA regulations for pharmaceutical and environmental safety. It is important to adhere to these guidelines to ensure safe handling, transport, and disposal.

Are there alternatives to Dermaseptin (CAS: 136212-91-4) in synthesis?

While Dermaseptin (CAS: 136212-91-4) is a unique antimicrobial peptide, alternatives include other antimicrobial peptides and small molecules. For instance, similar peptides like magainins and RNase 1 can serve as alternatives in certain applications, offering different structural and functional profiles.

What is the market or research trend for Dermaseptin (CAS: 136212-91-4)?

The market and research trend for Dermaseptin (CAS: 136212-91-4) are focused on its potential in antimicrobial therapy and wound healing. Recent studies highlight its effectiveness against drug-resistant bacteria and its potential for topical applications. The trend shows increasing interest in its use in medical devices and cosmetics.

How should waste containing Dermaseptin (CAS: 136212-91-4) be handled?

Waste containing Dermaseptin (CAS: 136212-91-4) should be collected in appropriate containers and handled according to local regulations. It is recommended to incinerate or use professional waste disposal services to ensure proper treatment and minimize environmental impact. Always follow safety precautions and consult with environmental agencies for specific guidelines.