[(2,2-Dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-[2-(L-alanylamino)-1,3-thiazol-4-yl]-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate | CAS No. 135821-54-4

[(2,2-Dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-[2-(L-alanylamino)-1,3-thiazol-4-yl]-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Basic Information

CAS Number

135821-54-4

Molecular Formula

C22H28N6O8S2

Molecular Weight

568.63 g/mol

AD

Basic Physical Properties

CC(C(=O)NC1=NC(=CS1)C(=NOC)C(=O)NC2C3N(C2=O)C(=CCS3)C(=O)OCOC(=O)C(C)(C)C)N

InChI

InChI=1S/C22H28N6O8S2/c1-10(23)15(29)26-21-24-11(8-38-21)13(27-34-5)16(30)25-14-17(31)28-12(6-7-37-18(14)28)19(32)35-9-36-20(33)22(2,3)4/h6,8,10,14,18H,7,9,23H2,1-5H3,(H,25,30)(H,24,26,29)/b27-13-/t10-,14+,18+/m0/s1

InChIKey

VOPANQNVVCPHQR-IVVGYLHBSA-N

LogP

0.15310000000000146

Topological Polar Surface Area

191.60999999999999 Ų

Hydrogen Bond Donor/Acceptor

4 / 14

Complexity

1050

Synonyms & References

English

  • 2,2-dimethylpropanoyloxymethyl (6R,7R)-7-[[(2Z)-2-[2-[[(2S)-2-aminopropanoyl]amino]-1,3-thiazol-4-yl]-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • UNII-3MM3320LJN
  • 3MM3320LJN
  • (+)-(Pivaloyloxy)methyl (6R,7R)-7-(2-(2-(L-alanylamino)thiazol-4-yl)glyoxylamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate 7(sup 2)-(Z)-(O)-methyloxime)
  • Ceftizoxime alapivoxil
  • (+)-(PIVALOYLOXY)METHYL (6R,7R)-7-(2-(2-(L-ALANYLAMINO)THIAZOL-4-YL)GLYOXYLAMIDO)-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLATE 72-(Z)-(O)-METHYLOXIME)
  • C21592
  • CHEMBL2106058
  • (2-(2-alanylaminothiazol-4-yl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylate
  • (+)-(Pivaloyloxy)methyl (6R,7R)-7-(2-(2-(L-alanylamino)thiazol-4-yl)glyoxylamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate 7,2-(Z)-(o)-methyloxime)
  • 135821-54-4
  • AS-924
  • Ceftizoxime alapivoxil [INN]
  • (Pivaloyloxy)methyl 7-((Z)-2-(2-((S)-2-aminopropanamido)thiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • 7-[[(2Z)-[2-[[(2S)-2-Amino-1-oxopropyl]amino]-4-thiazolyl](methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester

MDL Number

MFCD00895128

FAQ

What regulatory guidelines apply to [(2,2-Dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-[2-(L-alanylamino)-1,3-thiazol-4-yl]-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (CAS: 135821-54-4)?

This compound falls under various regulatory guidelines, including GHS (Global Harmonized System of Classification and Labeling of Chemicals) for hazard communication, REACH (Registration, Evaluation, Authorization, and Restriction of Chemicals) for EU compliance, and FDA/EPA requirements for pharmaceutical and environmental safety. Specific safety data sheets (SDS) and material safety data sheets (MSDS) must be consulted to ensure compliance with local and international regulations.

Are there alternatives to [(2,2-Dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-[2-(L-alanylamino)-1,3-thiazol-4-yl]-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (CAS: 135821-54-4) in synthesis?

While specific alternatives may vary, common isomers and analogs such as [(2,2-Dimethylpropanoyl)oxy]methyl (6S,7S)-7-{[(2Z)-2-[2-(L-alanylamino)-1,3-thiazol-4-yl]-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate or related amino acid derivatives can be used as alternatives. Substitutes like different amine functionalities can also be explored depending on the specific synthesis requirements.

What is the market or research trend for [(2,2-Dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-[2-(L-alanylamino)-1,3-thiazol-4-yl]-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (CAS: 135821-54-4)?

The market trend for this compound reflects increasing interest in novel therapeutic agents for specific diseases. Research is focusing on its potential applications in targeted drug delivery systems and as a scaffold for developing new drugs. Market trends suggest a growing demand from pharmaceutical companies for compounds with unique biological activities.

How should waste containing [(2,2-Dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-[2-(L-alanylamino)-1,3-thiazol-4-yl]-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (CAS: 135821-54-4) be handled?

Waste containing this compound should be collected and handled according to the local hazardous waste regulations. Proper disposal can involve incineration or professional waste disposal services. Environmental precautions include minimizing exposure to water sources and ensuring that waste is contained to prevent soil contamination. Always consult the latest safety data sheets (SDS) for specific handling instructions and regulatory requirements.

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