7-benzyl-2,7-diazaspiro[3.5]nonane

Basic Information

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CAS Number

135380-52-8

Molecular Formula

C14H20N2

Molecular Weight

216.33 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

323.5°C at 760 mmHg

Flash Point

131.7ºC

Refractive Index

1.592

SMILES

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C1CN(CCC12CNC2)CC3=CC=CC=C3

InChI

InChI=1S/C14H20N2/c1-2-4-13(5-3-1)10-16-8-6-14(7-9-16)11-15-12-14/h1-5,15H,6-12H2

InChIKey

SSKGDQBPVMFYNR-UHFFFAOYSA-N

LogP

1.8719999999999999

Topological Polar Surface Area

15.27 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

219

Synonyms & References

English

FT-0646906
MB08851
2,7-Diazaspiro[3.5]nonane,7-(phenylmethyl)-
BCP28160
7-Benzyl-2,7-diaza-spiro[3.5]nonane
MFCD10699448
DTXSID70657787
135380-52-8
SCHEMBL2306006
AKOS005264436
SSKGDQBPVMFYNR-UHFFFAOYSA-N
CS-D0629
7-benzyl-2,7-diazaspiro[3.5]nonane
AM20020430
AS-41446
2,7-Diazaspiro[3.5]nonane, 7-(phenylmethyl)-
7-Benzyl-2,7-diazaspiro[3.5]nonane
BH254
FC0234

MDL Number

MFCD10699448

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 7-benzyl-2,7-diazaspiro[3.5]nonane (CAS: 135380-52-8)?

7-benzyl-2,7-diazaspiro[3.5]nonane (CAS: 135380-52-8) has a crystalline form, with a molecular weight of approximately 214.26 g/mol. It is slightly soluble in common organic solvents like dimethyl sulfoxide (DMSO) and less soluble in water. This compound exhibits moderate reactivity, particularly towards nucleophiles and electrophiles, making it useful in organic synthesis.

How is 7-benzyl-2,7-diazaspiro[3.5]nonane (CAS: 135380-52-8) typically synthesized?

7-benzyl-2,7-diazaspiro[3.5]nonane (CAS: 135380-52-8) is typically synthesized via a multistep route involving the formation of a diazabicyclic intermediate. Common methods include a Wittig reaction followed by a Claisen condensation, yielding the desired product with good to excellent yield and high selectivity. Catalysts such as sodium hydride are often used for initial steps.

What industries use 7-benzyl-2,7-diazaspiro[3.5]nonane (CAS: 135380-52-8)?

7-benzyl-2,7-diazaspiro[3.5]nonane (CAS: 135380-52-8) finds applications in the pharmaceutical, polymer, and sensor industries. It is used as a precursor in the synthesis of pharmaceuticals and as a building block in the preparation of functional polymers. Additionally, due to its unique structure, it is explored for use in sensor applications and as a material in semiconductor devices.

What precautions should be taken when handling 7-benzyl-2,7-diazaspiro[3.5]nonane (CAS: 135380-52-8)?

When handling 7-benzyl-2,7-diazaspiro[3.5]nonane (CAS: 135380-52-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be used in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be handled with caution, using appropriate absorbents, and the area should be cleaned thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed safety information.