2-Cyanoethyl 6-[(trifluoroacetyl)amino]hexyl diisopropylphosphoramidoite | CAS No. 133975-85-6

2-Cyanoethyl 6-[(trifluoroacetyl)amino]hexyl diisopropylphosphoramidoite

Basic Information

CAS Number

133975-85-6

Molecular Formula

C17H31F3N3O3P

Molecular Weight

402.44 g/mol

AD

Basic Physical Properties

Solubility

Insuluble (1.0E-3 g/L) (25 ºC),

CC(C)N(C(C)C)P(OCCCCCCNC(=O)C(F)(F)F)OCCC#N

InChI

InChI=1S/C17H31F3N3O3P/c1-14(2)23(15(3)4)27(26-13-9-10-21)25-12-8-6-5-7-11-22-16(24)17(18,19)20/h14-15H,5-9,11-13H2,1-4H3,(H,22,24)

InChIKey

SMMKTKILBQHSFL-UHFFFAOYSA-N

LogP

5.014200000000004

Topological Polar Surface Area

50.8 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

459

Synonyms & References

English

  • TFA-Hexylaminolinker Phosphoramidite, configured for ABI
  • 5'-AMINO-MODIFIER-C 6-TFA CEP
  • Trifluoroacetyl-hexylamine-linker phosphoramidite
  • TFA-Hexylaminolinker Phosphoramidite
  • N-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]-2,2,2-trifluoroacetamide
  • Phosphoramidous acid,N,N-bis(1-methylethyl)-,2-cyanoethyl[6-[(2,2,2-trifluoroacetyl)amino]hexyl]ester
  • N-trifluoroacetyl (TFA)
  • C93417
  • SCHEMBL714350
  • N-(6-{[(2-CYANOETHOXY)(DIISOPROPYLAMINO)PHOSPHANYL]OXY}HEXYL)-2,2,2-TRIFLUOROACETAMIDE
  • 5'-Amino-Modifier C6-TFA CE Phosphoramidite
  • SMMKTKILBQHSFL-UHFFFAOYSA-N
  • R10-0011
  • 133975-85-6
  • AKOS015914432
  • C17H31F3N3O3P
  • 2-Cyanoethyl (6-(2,2,2-trifluoroacetamido)hexyl) diisopropylphosphoramidite
  • TFA-aminolinker C6 phosphoramidite
  • MFCD00797447
  • 2-Cyanoethyl(6-(2,2,2-trifluoroacetamido)hexyl)diisopropylphosphoramidite
  • Phosphoramidous acid,N,N-bis(1-methylethyl)-, 2-cyanoethyl [6-[(2,2,2-trifluoroacetyl)amino]hexyl]ester
  • 5’-AMINO-MODIFIER-C6-TFA CEP
  • Phosphoramidous acid,N,N-bis(1-methylethyl)-, 2-cyanoethyl [6-[(2,2,2-trifluoroacetyl)amino]he...
  • C6 TFA LINKER AMIDITE
  • trifluoroacetyl cyanoethyl phosphoramidite amino-linker
  • TFA-Hexylaminolinker Amidite
  • Aminolink 2
  • TFA-Aminolinker Amidite
  • TFA-Hexylaminolinker Phosphoramidite, configured for PerkinElmer, configured for Polygen
  • 5'-Amino-Modifier C6-TFA-phosphoramidite
  • N-[6-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxyhexyl]-2,2,2-trifluoro-acetamide

MDL Number

MFCD00797447

FAQ

What regulatory guidelines apply to 2-Cyanoethyl 6-[(trifluoroacetyl)amino]hexyl diisopropylphosphoramidoite (CAS: 133975-85-6)?

The compound 2-Cyanoethyl 6-[(trifluoroacetyl)amino]hexyl diisopropylphosphoramidoite (CAS: 133975-85-6) should comply with the regulations set forth by the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH in the European Union, and the requirements of the FDA and EPA in the United States. Manufacturers and importers must ensure that the compound is properly classified, labeled, and documented for safe handling and transport, and that it is registered with appropriate regulatory bodies.

Are there alternatives to 2-Cyanoethyl 6-[(trifluoroacetyl)amino]hexyl diisopropylphosphoramidoite in its synthesis?

While specific alternatives may vary depending on the exact application, researchers can explore the use of other phosphoramidites or related functional groups as alternatives in the synthesis of nucleic acid analogs. Common substitutes include 2-cyanoethyl diisopropylphosphoramidite and other protected nucleoside precursors, which can serve similar purposes in nucleic acid synthesis.

What is the market or research trend for 2-Cyanoethyl 6-[(trifluoroacetyl)amino]hexyl diisopropylphosphoramidoite?

The demand for 2-Cyanoethyl 6-[(trifluoroacetyl)amino]hexyl diisopropylphosphoramidoite (CAS: 133975-85-6) is driven by its applications in nucleic acid research, particularly in the synthesis of RNA and DNA analogs for therapeutic and diagnostic purposes. Research trends indicate a growing interest in developing more stable and functionalized nucleic acid molecules, which may drive further demand for specialized phosphoramidites like this compound.

How should waste containing 2-Cyanoethyl 6-[(trifluoroacetyl)amino]hexyl diisopropylphosphoramidoite (CAS: 133975-85-6) be handled?

Waste containing 2-Cyanoethyl 6-[(trifluoroacetyl)amino]hexyl diisopropylphosphoramidoite (CAS: 133975-85-6) should be collected in appropriate containers, labeled with the correct hazard information, and disposed of according to local regulations. Professional waste disposal services may be required for this compound due to its chemical properties. Environmental protection precautions, such as minimizing spillage and ensuring proper ventilation during handling, should also be taken to prevent contamination and exposure.

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