3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid

Basic Information

View in Editor

CAS Number

1334286-77-9

Molecular Formula

C7H14O5

Molecular Weight

178.18 g/mol

Basic Physical Properties

SMILES

View in Editor

OCCOCCOCCC(=O)O

InChI

InChI=1S/C7H14O5/c8-2-4-12-6-5-11-3-1-7(9)10/h8H,1-6H2,(H,9,10)

InChIKey

CMSNAEFYMNLDLU-UHFFFAOYSA-N

LogP

-0.5134000000000003

Topological Polar Surface Area

75.99 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

114

Synonyms & References

English

HO-2-COOH
Hydroxy-PEG2-acid

MDL Number

MFCD20646030

FAQ

What are the physical and chemical properties of 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid (CAS: 1334286-77-9)?

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid (CAS: 1334286-77-9) is a colorless or white crystalline solid with a molecular weight of approximately 288.34 g/mol. It has a high solubility in water and is slightly soluble in ethanol and methanol. It is highly reactive towards bases, showing basic properties. This compound is used in various applications requiring its specific functional groups and structural properties.

How is 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid (CAS: 1334286-77-9) typically synthesized?

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid is typically synthesized through a multi-step process involving acetylation, alkylation, and hydrolysis. The key steps involve the protection of the carboxylic acid functional group, followed by selective alkylation reactions to introduce the desired substituents. This synthesis route ensures high yield and good selectivity, with the use of standard organic solvents and mild conditions.

What industries use 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid (CAS: 1334286-77-9)?

3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid (CAS: 1334286-77-9) is used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients due to its functional groups. It is also found in the polymer industry as a monomer for the development of biocompatible polymers. Additionally, it is used in sensor technology and semiconductor manufacturing for its specific chemical properties.

What precautions should be taken when handling 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid (CAS: 1334286-77-9)?

When handling 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid (CAS: 1334286-77-9), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Ensure proper storage in a cool, dry place away from heat sources and incompatible materials. In case of spills, neutralize with an appropriate base and then clean up carefully. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.