(3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine ethanedioate (1:1)

Basic Information

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CAS Number

132335-47-8

Molecular Formula

C21H23NO5S

Molecular Weight

401.48 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

459.7°C at 760 mmHg

SMILES

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CN(C)CCC(C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.C(=O)(C(=O)O)O

InChI

InChI=1S/C19H21NOS.C2H2O4/c1-20(2)13-12-18(19-11-6-14-22-19)21-17-10-5-8-15-7-3-4-9-16(15)17;3-1(4)2(5)6/h3-11,14,18H,12-13H2,1-2H3;(H,3,4)(H,5,6)/t18-;/m0./s1

InChIKey

GYUDMXKAVMKVPS-FERBBOLQSA-N

LogP

4.128700000000002

Topological Polar Surface Area

87.07000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

407

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

SCHEMBL1535363
MFCD08458302
EN300-7372592
AKOS015895978
GYUDMXKAVMKVPS-FERBBOLQSA-N
(S)-N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine oxalate
DS-17898
S-(+)-N,N-Dimethyl-3-(1-naphthoxy)-3-(2-thienyl)-propylamine Oxalate
(3S)-N,N-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;oxalic acid
2-Thiophenepropanamine, N,N-dimethyl-gamma-(1-naphthalenyloxy)-, ethanedioate (1:1), (gammaS)-
(3S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate
(3S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine Oxalate (N-Methylduloxetine Oxalate)
(S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amineoxalate
J-006164
CS-0151301
(S)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine oxalate
C21H23NO5S
S-(+)-N,N-Dimethyl-3-(1-naphthoxy)-3-(2-thienyl)-1-propylamine oxalate
(S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine oxalate
DTXSID20474380
132335-47-8
N-Methyl Duloxetine Oxalate
Oxalic acid--(3S)-N,N-dimethyl-3-[(naphthalen-1-yl)oxy]-3-(thiophen-2-yl)propan-1-amine (1/1)
AC-31110
DIMETHYL[(3S)-3-(NAPHTHALEN-1-YLOXY)-3-(THIOPHEN-2-YL)PROPYL]AMINE; OXALIC ACID
S-(+)-N1N-DIMETHYL-3-(1-NAPHTHALENYLOXY)-3-(2-THIENYL)-1-PROPANAMINE OXALATE
(S)-(+)-N,N-Dimethyl-3-(1-Naphthalenyloxy)-3-(2-Thinyl)Propanamine Oxalate
S-(+)-N,N-Dimethyl-3-(1-Naphthalenyloxy)-3-(2-thienyl)-1-propanamine oxalate
Duloxetine intermediate
(S)-(+)-N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-propanamine oxalate
S-(+)-N,N-Dimethyl-3-(1-naphthoxy)-3-(2-thienyl)propylamine Oxalate

MDL Number

MFCD08458302

Customs Code

2934999090

FAQ

What regulatory guidelines apply to (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine ethanedioate (1:1) (CAS: 132335-47-8)?

The compound (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine ethanedioate (1:1) (CAS: 132335-47-8) is subject to various regulatory guidelines including GHS classification for hazardous chemicals, REACH regulations for EU importers, and FDA/EPA requirements for chemical safety in the US. Specific handling and storage guidelines should comply with local and international regulations.

Are there alternatives to (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine ethanedioate (1:1) (CAS: 132335-47-8) in synthesis?

There are several alternatives to (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine ethanedioate (1:1) (CAS: 132335-47-8) in synthesis, such as similar thienyl-containing compounds or naphthyl-substituted derivatives. Common alternative reagents include thiosemicarbazides and other amines. However, the choice of alternative depends on the specific requirements of the synthesis and the desired product properties.

What is the market or research trend for (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine ethanedioate (1:1) (CAS: 132335-47-8)?

The market for (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine ethanedioate (1:1) (CAS: 132335-47-8) is currently stable, with a focus on its use in pharmaceutical and chemical research. Emerging trends include the exploration of its properties in medicinal chemistry and potential applications in novel drug development. Research is also investigating its reactivity in various synthetic pathways.

How should waste containing (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine ethanedioate (1:1) (CAS: 132335-47-8) be handled?

Waste containing (3S)-N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine ethanedioate (1:1) (CAS: 132335-47-8) should be collected in appropriate containers and stored separately from other waste. Proper disposal should follow local regulations and may involve incineration or professional waste disposal services. Ensure all safety precautions are taken to prevent environmental contamination during handling and disposal.