Human beta-amyloid peptide (1-40)

Basic Information

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CAS Number

131438-79-4

Molecular Formula

C67H142N25O6

Molecular Weight

1394.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

H2O: ~6 mg/mL

SMILES

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CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CNC=N3)NC(=O)C(CC4=CNC=N4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC6=CNC=N6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N

InChI

InChI=1S/C67H142N25O6/c1-52(2)41-60(48-92-63(54(5)6)49-81-24-23-73-7)90-45-56(11-8-9-19-68)89-46-58(13-16-64(70)94)85-37-32-77-27-30-82-50-62(53(3)4)91-47-59(15-18-66(97)98)86-38-33-75-26-29-79-44-61(51-93)87-39-34-76-25-28-78-42-55(12-10-21-88-67(71)72)83-40-35-80-43-57(14-17-65(95)96)84-36-31-74-22-20-69/h7,20,24,28,30-35,52-63,73-87,89-93H,8-19,21-23,25-27,29,36-51,68-69H2,1-6H3,(H2,70,94)(H,95,96)(H,97,98)(H4,71,72,88)/t55-,56-,57-,58-,59-,60-,61+,62+,63+/m0/s1

InChIKey

IURQNTVTURLVBX-IQACJYPTSA-N

LogP

-3.672629999999939

Topological Polar Surface Area

480.42999999999984 Å²

Hydrogen Bond Donor/Acceptor

32 / 31

Complexity

10500

Synonyms & References

English

Abeta40
Amyloid beta peptide(1-40) (synthetic)
Abeta40 [MI]
EX-A7736
Amyloid ?-Peptide (1-40) (human)
UNII-13539D6GO8
Beta-Amyloid(1-40)
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Abeta(1-40)
Beta-amyloid protein 40
Human beta-amyloid peptide (1-40)
AKOS024456454
beta-Amyloid protein(1-40)
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
CHEBI:64646
beta-amyloid 40
131438-79-4
Human beta-amyloid peptide-(1-40)
Amyloid beta-Peptide 1-40 TFA
beta-Amyloid 1-40
13539D6GO8
beta-Amyloid (1-40)
Amyloid beta-protein fragment 1-40
Amyloid β Protein Fragment 1-40
Amyloid β -Protein (1-40)
Amyloid beta-Protein (Human, 1-40)
AMYLOID BETA-PROTEIN (HUMAN, 1-40) TRIFLUOROACETATE
Amyloid β-Peptide (1-40) (human)
Amyloid β-Protein (1-40) (HFIP-treated)
B-AMYLOID, FRAGMENT 1-40
Amyloidb-peptide(1-40)(human)

MDL Number

MFCD00130509

FAQ

What regulatory guidelines apply to Human beta-amyloid peptide (1-40) (CAS: 131438-79-4)?

Human beta-amyloid peptide (1-40) (CAS: 131438-79-4) is subject to various regulatory guidelines. It must comply with the Globally Harmonized System (GHS) for Classification and Labelling of Chemicals, ensuring appropriate hazard communication. In the European Union, it is regulated under the REACH法规，确保化学品的注册、评估、许可和限制。此外，美国食品药品监督管理局（FDA）和环境保护署（EPA）也有相关的安全和环境要求。

Are there alternatives to Human beta-amyloid peptide (1-40) (CAS: 131438-79-4) in synthesis?

For the synthesis of Human beta-amyloid peptide (1-40) (CAS: 131438-79-4), there are alternative reagents and approaches. Commonly used methods include solid-phase peptide synthesis and solution-phase synthesis. Additionally, analogs such as shorter peptides or modified sequences can serve as viable alternatives in certain applications.

What is the market or research trend for Human beta-amyloid peptide (1-40) (CAS: 131438-79-4)?

The market for Human beta-amyloid peptide (1-40) (CAS: 131438-79-4) is driven by ongoing research in Alzheimer's disease, with a focus on potential therapeutic applications. Research trends include developing new delivery methods and understanding the molecular mechanisms of the peptide. Market dynamics are influenced by funding for Alzheimer's research and the potential for new treatments.

How should waste containing Human beta-amyloid peptide (1-40) (CAS: 131438-79-4) be handled?

Waste containing Human beta-amyloid peptide (1-40) (CAS: 131438-79-4) should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration is a common method, but it must be conducted under controlled conditions to ensure safety and environmental compliance. Environmental protection measures include minimizing exposure and ensuring proper disposal to prevent contamination.