Erythromycin, 9-oxime

Basic Information

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CAS Number

13127-18-9

Molecular Formula

C37H68N2O13

Molecular Weight

748.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

155-165°C

Refractive Index

1.55

SMILES

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CCC1C(C(C(C(=NO)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O

InChI

InChI=1S/C37H68N2O13/c1-14-25-37(10,45)30(41)20(4)27(38-46)18(2)16-35(8,44)32(52-34-28(40)24(39(11)12)15-19(3)48-34)21(5)29(22(6)33(43)50-25)51-26-17-36(9,47-13)31(42)23(7)49-26/h18-26,28-32,34,40-42,44-46H,14-17H2,1-13H3/b38-27+/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

InChIKey

KYTWXIARANQMCA-ZTILBQITSA-N

LogP

2.0467000000000035

Topological Polar Surface Area

209.42999999999998 Å²

Hydrogen Bond Donor/Acceptor

6 / 15

Complexity

1210

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Erythromycin-9-oxime
Erythromycin A oxime
MFCD08062410
NS00077329
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one
Erythromycin Impurity J
SCHEMBL13615734
13127-18-9
J-005969
111321-02-9
Erythromycin oxime
Roxithromycin Impurity C
Clarithromycin EP Impurity J
(E)-Erythromycin oxime
Erythromycin A 9-Oxime (E)
Erythromycin A Oxime
Erythromycin A Oxime (Roxithromycin Impurity C)
ERYTHROMYCIN-9-OXIME
RU-28111
UNII-10W452CMTZ
ERYTHROMYCIN A 9-OXIME
9-O-Erythromycin oxime
9-ErythroMycin 9-OxiMe
9-ErythroMycin A OxiMe
RoxithroMycin IMpurity C
Clarithromycin Impurity J
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one

MDL Number

MFCD00914803

Customs Code

29415000

FAQ

What regulatory guidelines apply to Erythromycin, 9-oxime (CAS: 13127-18-9)?

Erythromycin, 9-oxime (CAS: 13127-18-9) is subject to various regulatory guidelines including the GHS classification for hazardous chemicals, REACH regulations for European Union member states, and FDA/EPA requirements for use in pharmaceuticals and agricultural applications. Compliance with local and international safety standards is essential to ensure product safety and environmental protection.

Are there alternatives to Erythromycin, 9-oxime in synthesis?

In synthesis, alternative reagents such as 9-oxoerythromycin A and other macrolides can be considered as alternatives to Erythromycin, 9-oxime. These compounds offer similar antimicrobial properties but may have different advantages in terms of reaction conditions and product yields.

What is the market or research trend for Erythromycin, 9-oxime (CAS: 13127-18-9)?

The market for Erythromycin, 9-oxime (CAS: 13127-18-9) reflects a growing interest in advanced antimicrobial agents. Research trends include the development of more potent derivatives and the exploration of its application in novel therapeutic areas such as infectious diseases and inflammatory conditions. Market trends suggest increasing demand driven by rising healthcare costs and the need for effective antibiotics.

How should waste containing Erythromycin, 9-oxime (CAS: 13127-18-9) be handled?

Waste containing Erythromycin, 9-oxime (CAS: 13127-18-9) should be collected and handled according to local regulations, typically involving the use of a professional waste disposal service. Incineration is a common method for disposing of hazardous waste, and environmental protection measures should be taken to prevent contamination of soil and water. Proper storage and transportation of waste are also crucial to maintain safety and prevent accidental spills or releases.