11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one | CAS No. 129618-40-2

11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

Basic Information

CAS Number

129618-40-2

Molecular Formula

C15H14N4O

Molecular Weight

266.3 g/mol

AD

Basic Physical Properties

Physical State

Powder

Melting Point

244.0 to 248.0 deg-C

Boiling Point

415.4°C at 760 mmHg

Flash Point

205℃

Solubility

DMSO: ≥22mg/mL

Refractive Index

1.6200 (estimate)

CC1=C2C(=NC=C1)N(C3=C(C=CC=N3)C(=O)N2)C4CC4

InChI

InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)

InChIKey

NQDJXKOVJZTUJA-UHFFFAOYSA-N

LogP

2.6512200000000004

pKa

2.8(at 25℃)

Topological Polar Surface Area

58.120000000000005 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

397

Safety Information

View Safety Information

GHS Hazard Pictograms

H302H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

  • BIRG 587
  • NEVIRAPINE [ORANGE BOOK]
  • KS-5019
  • NCGC00065890-04
  • AB00393001_17
  • 2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0,3,8]pentadeca-1(15),3(8),4,6,11,13-hexaen-10-one
  • 6H-Dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-methyl-
  • Nevirapine (anhydrous), European Pharmacopoeia (EP) Reference Standard
  • Viramune XR
  • Tox21_110982_1
  • BI-RG-587; BIRG 0587; BIRG587; HSDB 7164; NSC 641530; NVP
  • Nevirapine for peak identification, European Pharmacopoeia (EP) Reference Standard
  • NEVIRAPINE [USP MONOGRAPH]
  • NEVIRAPINE [JAN]
  • 11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • Nevirapine for peak identification
  • 2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
  • NSC641530
  • HMS2051J09
  • Nevirapine,(S)
  • N11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e]-[1,4]diazepin-6-one & CD4-immunoadhesin
  • GTPL12676
  • Nevirapine 100 microg/mL in Acetonitrile
  • NCGC00065890-03
  • 11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[2,3-e:3',2'-b][1,4]diazepin-6-one & PRO 140 (Anti-CCR5 monoclonal antibody)
  • DTXSID7031797
  • NEVIRAPINE [USAN]
  • NCGC00065890-02
  • HMS3371E03
  • Viramune(TM)
  • 6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-

MDL Number

MFCD00866928

Customs Code

2934994000

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