Growth Hormone, Human, recombinant (rh des-pheGH)

Basic Information

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CAS Number

12629-01-5

Molecular Formula

C81H127N19O21S

Molecular Weight

1735.09 g/mol

EINECS

235-735-8

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Specific Rotation

25 -38.7° (0.1M acetic acid)

SMILES

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CCC(C)C(C(=O)N1CCCC1C(=NC(CC(C)C)C(=NC(CO)C(=NC(CCCNC(=N)N)C(=NC(CC(C)C)C(=NC(Cc2ccccc2)C(=NC(CC(=O)O)C(=NC(CC(=N)O)C(=NC(C)C(=NC(CCSC)C(=NC(CC(C)C)C(=O)O)O)O)O)O)O)O)O)O)O)O)N=C(C(C(C)O)N=C(C3CCCN3C(=O)C(Cc4ccccc4)N)O)O

InChI

InChI=1S/C81H127N19O21S/c1-12-45(8)64(97-77(117)65(47(10)102)98-76(116)61-28-20-31-99(61)78(118)50(82)37-48-22-15-13-16-23-48)79(119)100-32-21-27-60(100)75(115)94-54(35-43(4)5)71(111)96-59(41-101)74(114)89-51(26-19-30-86-81(84)85)67(107)90-53(34-42(2)3)70(110)91-55(38-49-24-17-14-18-25-49)72(112)93-57(40-63(104)105)73(113)92-56(39-62(83)103)69(109)87-46(9)66(106)88-52(29-33-122-11)68(108)95-58(80(120)121)36-44(6)7/h13-18,22-25,42-47,50-61,64-65,101-102H,12,19-21,26-41,82H2,1-11H3,(H2,83,103)(H,87,109)(H,88,106)(H,89,114)(H,90,107)(H,91,110)(H,92,113)(H,93,112)(H,94,115)(H,95,108)(H,96,111)(H,97,117)(H,98,116)(H,104,105)(H,120,121)(H4,84,85,86)

InChIKey

GXPXOZHEDPXXKH-UHFFFAOYSA-N

LogP

7.76074

Topological Polar Surface Area

678.7600000000003 Å²

Hydrogen Bond Donor/Acceptor

24 / 40

Complexity

478

Safety Information

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Toxicity

LD50 oral in rat: 160iu/kg

Synonyms & References

English

Recombinant human somatotropin
Somatropin (8.63 USP Somatropin Units/vial) (INTERNATIONAL COLD CHAIN SHIPMENT REQUIRED)
SoMatotropin (huMan)(9CI)
Growth hormone 1
Growth Hormone from chicken
HGH high quality Cas no.:12629-01-5
HGH somatropin CAS12629-01-5 Human Growth Hormone
cb311
Somatotropin
Human growth hormone
GROWTH HORMONE, HUMAN
SOMATROPIN (RHGH), 3IU
STH
HGH
sj0011
D02691
ly137998
Nutropin
humatrope
crecormon
GH
Growth Hormone, Human, recombinant (rh des-pheGH)

EC Number

235-735-8

Customs Code

2937110000

FAQ

What is Growth Hormone, Human, recombinant (rh des-pheGH) (CAS: 12629-01-5)?

Growth Hormone, Human, recombinant (rh des-pheGH) is a synthetic version of human growth hormone (hGH) with a modified amino terminal sequence. It is a protein hormone used to stimulate growth and cell reproduction. The compound has a molecular weight of approximately 22,130 Da and is produced through recombinant DNA technology.

What are the main uses of Growth Hormone, Human, recombinant (rh des-pheGH) (CAS: 12629-01-5)?

Growth Hormone, Human, recombinant (rh des-pheGH) is primarily used to treat growth hormone deficiency in children and adults, short stature in children, and certain types of chronic kidney disease. It is also used in clinical research and for improving muscle mass and strength in adults with HIV/AIDS.

Is Growth Hormone, Human, recombinant (rh des-pheGH) (CAS: 12629-01-5) safe?

Growth Hormone, Human, recombinant (rh des-pheGH) is generally considered safe when used as directed by a healthcare provider. However, it may cause side effects such as joint pain, carpal tunnel syndrome, and glucose intolerance. Patients should follow their doctor's advice and adhere to prescribed dosages to minimize risks.

How should Growth Hormone, Human, recombinant (rh des-pheGH) (CAS: 12629-01-5) be stored?

Store Growth Hormone, Human, recombinant (rh des-pheGH) in a refrigerator between 2-8°C (36-46°F). Do not freeze the product. Protect it from light and keep it in its original container to maintain its stability. It should be used within 14 days after reconstitution at room temperature if not refrigerated.