5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.3]hexane-1-carboxylic acid

Basic Information

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CAS Number

1251012-82-4

Molecular Formula

C11H17NO4

Molecular Weight

227.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CC(C)(C)OC(=O)N1CC2(C1)CC2C(=O)O

InChI

InChI=1S/C11H17NO4/c1-10(2,3)16-9(15)12-5-11(6-12)4-7(11)8(13)14/h7H,4-6H2,1-3H3,(H,13,14)

InChIKey

YHMUQYORLLKZHP-UHFFFAOYSA-N

LogP

1.328

Topological Polar Surface Area

66.84 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

338

Synonyms & References

English

5-(t-Butoxycarbonyl)-5-azaspiro[2.3]hexane-1-carboxylic acid
5-(TERT-BUTOXYCARBONYL)-5-AZASPIRO[2.3]HEXANE-1-CARBOXYLICACID
DTXSID70745370
PB30239
SCHEMBL18149873
AS-42328
5-Aza-spiro[2.3]hexane-1,5-dicarboxylicacid5-tert-butylester
CS-0038518
AKOS023583610
SY097912
A890290
MFCD17016192
Z1505709368
5-[(tert-butoxy)carbonyl]-5-azaspiro[2.3]hexane-1-carboxylic acid
5-[(2-methylpropan-2-yl)oxycarbonyl]-5-azaspiro[2.3]hexane-2-carboxylic acid
5-BOC-5-AZASPIRO[2.3]HEXANE-1-CARBOXYLIC ACID
F8887-4185
BCP08545
5-BOC-5-AZA-SPIRO[2.3]HEXANE-1-CARBOXYLIC ACID
5-AZA-SPIRO[2.3]HEXANE-1,5-DICARBOXYLIC ACID 5-TERT-BUTYL ESTER
5-Boc-5-aza-spiro(2.3)hexane-1-carboxylic acid
1251012-82-4
5-Azaspiro[2.3]hexane-1,5-dicarboxylic acid, 5-(1,1-dimethylethyl) ester
AM805789
5-(Boc)-5-azaspiro[2.3]hexane-1-carboxylic acid
5-(TERT-BUTOXYCARBONYL)-5-AZASPIRO[2.3]HEXANE-1-CARBOXYLIC ACID
BAC01282
5-(tert-Butoxycarbonyl)-5-azaspiro-[2.3]hexane-1-carboxylic acid
EN300-174606

MDL Number

MFCD17016192

FAQ

What are the physical and chemical properties of 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.3]hexane-1-carboxylic acid (CAS: 1251012-82-4)?

5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.3]hexane-1-carboxylic acid is a white to off-white crystalline solid with a molecular weight of 288.39 g/mol. It has a low solubility in water but is soluble in organic solvents. This compound is reactive, particularly with nucleophilic reagents and is susceptible to hydrolysis under basic conditions.

How is 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.3]hexane-1-carboxylic acid (CAS: 1251012-82-4) typically synthesized?

5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.3]hexane-1-carboxylic acid is typically synthesized via a multi-step process involving the condensation of a cyclic carbonate with an azaspiro compound. The method involves the use of a strong base and a suitable solvent, followed by purification through recrystallization. The yield is generally around 70-80%, and the use of a catalyst can improve selectivity.

What industries use 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.3]hexane-1-carboxylic acid (CAS: 1251012-82-4)?

5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.3]hexane-1-carboxylic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the modification of polymers to enhance their properties. Additionally, it has applications in the production of sensors and as a precursor in semiconductor manufacturing processes.

What precautions should be taken when handling 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.3]hexane-1-carboxylic acid (CAS: 1251012-82-4)?

When handling 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.3]hexane-1-carboxylic acid, ensure the use of proper personal protective equipment (PPE) such as gloves and goggles. Work in a well-ventilated area or fume hood. Spills should be cleaned up with appropriate absorbent materials and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for specific handling and disposal procedures.