2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride (1:1)

Basic Information

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CAS Number

124763-51-5

Molecular Formula

C8H20ClNO5

Molecular Weight

245.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Boiling Point

484.2°C at 760 mmHg

SMILES

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C(CO)N(CCO)C(CO)(CO)CO.Cl

InChI

InChI=1S/C8H19NO5.ClH/c10-3-1-9(2-4-11)8(5-12,6-13)7-14;/h10-14H,1-7H2;1H

InChIKey

VEYRVLHAMHQVTC-UHFFFAOYSA-N

LogP

-2.5894999999999984

Topological Polar Surface Area

104.39000000000001 Å²

Hydrogen Bond Donor/Acceptor

5 / 6

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

bis-tris hydrochloride
2-(Bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)propane-1,3-diol hydrochloride
BIS TRIS HYDROCHLORIDE
BIS-TRIS-HCL
2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol
2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol,hydrochloride
2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride
2- [bis (2-hydroxyethyl) amino] -2- (hydroxymethyl) -1,3-propanediol hydrochloride

MDL Number

MFCD00171252

FAQ

What is 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride (CAS: 124763-51-5)?

2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride, with CAS number 124763-51-5, is a water-soluble, non-toxic compound. It is an amino alcohol derivative with a pKa of approximately 8. It has a faintly sweet taste and is commonly used in pharmaceuticals and cosmetics due to its buffering and pH adjustment properties.

What are the main uses of 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride (CAS: 124763-51-5)?

2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride is widely used in pharmaceuticals for its buffering and pH adjustment properties. It is also used in cosmetics as a moisturizer and in food industries as a pH stabilizer and preservative. Additionally, it finds applications in research and development, particularly in formulating buffers and stabilizers for biological and chemical assays.

Is 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride (CAS: 124763-51-5) safe?

Yes, 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride (CAS: 124763-51-5) is considered safe for use in pharmaceuticals, cosmetics, and food products. It is non-toxic, non-irritating, and does not pose a significant risk to human health when used as directed. However, appropriate handling and storage procedures should be followed to ensure safety.

How should 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride (CAS: 124763-51-5) be stored?

2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride (CAS: 124763-51-5) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture absorption. The storage temperature should not exceed 25°C (77°F) to maintain its stability. Avoid contact with incompatible materials and ensure proper ventilation during handling.