Alirocumab | CAS No. 1245916-14-6

Alirocumab

Basic Information

CAS Number

1245916-14-6

Molecular Formula

C3H9Na2O6P

Molecular Weight

218.05 g/mol

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Basic Physical Properties

C(C(COP(=O)(O)O)O)O.[Na].[Na]

InChI

InChI=1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;

InChIKey

CATWCRUATKKAAQ-UHFFFAOYSA-N

LogP

-2.3127

Topological Polar Surface Area

107.22000000000001 Ų

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

129

Synonyms & References

English

  • Alirocumab
  • Praluent
  • REGN 727
  • SAR 236553
  • BCP25199
  • CID 88214187

FAQ

What is alirocumab (CAS: 1245916-14-6)?

Alirocumab (CAS: 1245916-14-6) is a monoclonal antibody used to lower cholesterol levels in patients with high cholesterol, particularly those with familial hypercholesterolemia or those unable to tolerate statins.

What are the main uses of alirocumab (CAS: 1245916-14-6)?

Alirocumab (CAS: 1245916-14-6) is primarily used for the treatment of heterozygous familial hypercholesterolemia and as an adjunct to maximally tolerated statin therapy in adults to reduce low-density lipoprotein cholesterol (LDL-C).

Is alirocumab (CAS: 1245916-14-6) safe?

Alirocumab (CAS: 1245916-14-6) is generally considered safe. However, it may cause side effects such as injection site reactions, headache, and nausea. Patients should inform their healthcare provider if they experience any unusual symptoms.

How should alirocumab (CAS: 1245916-14-6) be stored?

Alirocumab (CAS: 1245916-14-6) should be stored at 2°C to 8°C (36°F to 46°F) in the refrigerator. It should be kept away from light and not frozen. The medication should be protected from excessive heat and humidity. Do not shake the vial before use.

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