2-Chloro-4-methyl-5-pyrimidinol

Basic Information

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CAS Number

1245506-62-0

Molecular Formula

C5H5ClN2O

Molecular Weight

144.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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Cc1c(cnc(n1)Cl)O

InChI

InChI=1S/C5H5ClN2O/c1-3-4(9)2-7-5(6)8-3/h2,9H,1H3

InChIKey

WGAAADFJSILTKG-UHFFFAOYSA-N

LogP

1.14402

Topological Polar Surface Area

46.010000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Synonyms & References

English

2-chloro-4-methyl-5-Pyrimidinol
2-Chloro-5-hydroxy-4-methylpyrimidine
2-chloro-4-methylpyrimidin-5-ol

MDL Number

MFCD16659710

FAQ

What are the physical and chemical properties of 2-Chloro-4-methyl-5-pyrimidinol (CAS: 1245506-62-0)?

2-Chloro-4-methyl-5-pyrimidinol (CAS: 1245506-62-0) is a crystalline solid with a molecular weight of approximately 165.01 g/mol. It has a low water solubility, making it poorly soluble in water. This compound is reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored away from moisture and oxidizing agents.

How is 2-Chloro-4-methyl-5-pyrimidinol (CAS: 1245506-62-0) typically synthesized?

2-Chloro-4-methyl-5-pyrimidinol (CAS: 1245506-62-0) is typically synthesized through the reduction of 2-chloro-4-methyl-5-pyrimidone with sodium borohydride. The reaction yields a high purity product with good selectivity and yields. The process should be conducted in a well-ventilated area with appropriate safety measures in place.

What industries use 2-Chloro-4-methyl-5-pyrimidinol (CAS: 1245506-62-0)?

2-Chloro-4-methyl-5-pyrimidinol (CAS: 1245506-62-0) is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a precursor for the preparation of various polymers. Additionally, it is utilized in the production of sensors and semiconductors.

What precautions should be taken when handling 2-Chloro-4-methyl-5-pyrimidinol (CAS: 1245506-62-0)?

When handling 2-Chloro-4-methyl-5-pyrimidinol (CAS: 1245506-62-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and laboratory coat. The compound should be stored in a well-ventilated area, and the use of a fume hood is recommended during handling. Proper spill cleanup procedures should be followed, and the material safety data sheet (MSDS) should be consulted for detailed safety information.