N,N'-(10,17-Dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis{3-[(4S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydro-4-isoquinolinyl]benzenesulfonamide}

Basic Information

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CAS Number

1234423-95-0

Molecular Formula

C50H66Cl4N8O10S2

Molecular Weight

1145.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

Practically insoluble

SMILES

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CN1Cc2c(cc(cc2Cl)Cl)[C@@H](C1)c3cccc(c3)S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)c4cccc(c4)[C@@H]5CN(Cc6c5cc(cc6Cl)Cl)C

InChI

InChI=1S/C50H66Cl4N8O10S2/c1-61-31-43(41-27-37(51)29-47(53)45(41)33-61)35-7-5-9-39(25-35)73(65,66)59-15-19-71-23-21-69-17-13-57-49(63)55-11-3-4-12-56-50(64)58-14-18-70-22-24-72-20-16-60-74(67,68)40-10-6-8-36(26-40)44-32-62(2)34-46-42(44)28-38(52)30-48(46)54/h5-10,25-30,43-44,59-60H,3-4,11-24,31-34H2,1-2H3,(H2,55,57,63)(H2,56,58,64)/t43-,44-/m0/s1

InChIKey

DNHPDWGIXIMXSA-CXNSMIOJSA-N

LogP

6.156600000000009

Topological Polar Surface Area

217.99999999999997 Å²

Hydrogen Bond Donor/Acceptor

6 / 18

Complexity

1770

Synonyms & References

English

Tenapanor
AZD 1722
AZD-1722
RDX5791
RDX-5791
17-[[[3-[(4S)-6,8-Dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]-N-[2-[2-[2-[[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]ethoxy]ethoxy]ethyl]-8-oxo-12,15-dioxa-2,7,9-triazaheptadecanamide
AZD1722
Tenapanor free base
WYD79216A6
RDX 5791
Tenapanor [USAN:INN]
Ibsrela
Tenapanor (USAN/INN)
GTPL8449
BDBM381823
BCP24892
B

MDL Number

MFCD28386333

FAQ

What regulatory guidelines apply to N,N'-(10,17-Dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis{3-[(4S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydro-4-isoquinolinyl]benzenesulfonamide} (CAS: 1234423-95-0)?

This compound falls under regulatory guidelines as outlined by the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH for European manufacturers and importers, and may require FDA/EPA registration in the United States. Specific handling and disposal guidelines are also provided by OSHA and other local safety authorities.

Are there alternatives to N,N'-(10,17-Dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis{3-[(4S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydro-4-isoquinolinyl]benzenesulfonamide} (CAS: 1234423-95-0) in synthesis?

There are various alternatives such as isomers and analogs like N,N'-(10,17-Dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis{3-[(4R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydro-4-isoquinolinyl]benzenesulfonamide}, or alternative reagents like dichloroacetamide or other sulfonamides. These alternatives may offer similar or improved properties depending on the specific application.

What is the market or research trend for N,N'-(10,17-Dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis{3-[(4S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydro-4-isoquinolinyl]benzenesulfonamide} (CAS: 1234423-95-0)?

This compound is currently under research for its potential in pharmaceutical applications, particularly in the treatment of certain diseases. Market trends indicate increasing interest in its use as a novel therapeutic agent, with ongoing studies focusing on its efficacy and safety profiles. The compound is also being explored in other fields such as materials science and as a precursor in complex organic synthesis.

How should waste containing N,N'-(10,17-Dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis{3-[(4S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydro-4-isoquinolinyl]benzenesulfonamide} (CAS: 1234423-95-0) be handled?

Waste containing this compound should be collected in appropriate containers and stored in a secure manner to prevent environmental contamination. It is recommended to use professional waste disposal services for incineration or other environmentally safe methods. Proper personal protective equipment (PPE) should be worn during handling, and all disposal activities should comply with local and national regulations to ensure environmental safety.