FMOC-D-4-CARBAMOYLPHE

Basic Information

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CAS Number

1217610-39-3

Molecular Formula

C25H22N2O5

Molecular Weight

430.45 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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O=C(N[C@@H](C(=O)O)Cc1ccc(cc1)C(=O)N)OCC1c2ccccc2c2c1cccc2

InChI

InChI=1S/C25H22N2O5/c26-23(28)16-11-9-15(10-12-16)13-22(24(29)30)27-25(31)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H2,26,28)(H,27,31)(H,29,30)/t22-/m1/s1

InChIKey

MUNGLNMRFZUOTD-JOCHJYFZSA-N

LogP

3.3199000000000014

Topological Polar Surface Area

118.72 Å²

Hydrogen Bond Donor/Acceptor

4 / 7

Complexity

668

Synonyms & References

English

Fmoc-d-4-carbamoylphenylalanine
Fmoc-D-4-Carbamoylphe
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-carbamoylphenyl)propanoic acid
(2R)-3-(4-carbamoylphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
(2R)-3-(4-carbamoylphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propionic acid
(2R)-3-(4-carbamoylphenyl)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]propanoic acid
(2R)-3-(4-aminocarbonylphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
Fmoc-D-4-carba

MDL Number

MFCD06659137

FAQ

What are the physical and chemical properties of FMOC-D-4-CARBAMOYLPHE (CAS: 1217610-39-3)?

FMOC-D-4-CARBAMOYLPHE is a crystalline compound with a molecular weight of approximately 326.36 g/mol. It has poor water solubility but is soluble in organic solvents like DMF and DMSO. It exhibits reactivity towards nucleophiles and is often used in peptide synthesis due to its protecting group properties.

How is FMOC-D-4-CARBAMOYLPHE (CAS: 1217610-39-3) typically synthesized?

FMOC-D-4-CARBAMOYLPHE is synthesized through the sequential addition of D-alanine and carbamoyl group to the FMOC-protected amino acid. The process involves the use of coupling agents like HATU, and the reaction is typically carried out in the presence of a base such as DIPEA to achieve high yield and selectivity.

What industries use FMOC-D-4-CARBAMOYLPHE (CAS: 1217610-39-3)?

FMOC-D-4-CARBAMOYLPHE is widely used in the pharmaceutical industry for peptide synthesis. It is also utilized in the development of polymers and sensors. Additionally, it is applied in the semiconductor industry for certain chemical processes.

What precautions should be taken when handling FMOC-D-4-CARBAMOYLPHE (CAS: 1217610-39-3)?

When handling FMOC-D-4-CARBAMOYLPHE, it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up using appropriate absorbents, and the Material Safety Data Sheet (MSDS) should be consulted for specific disposal instructions.