4-Acetamidobenzenesulfonyl chloride

Basic Information

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CAS Number

121-60-8

Molecular Formula

C8H8ClNO3S

Molecular Weight

233.68 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

142-145 °C (dec.)

Boiling Point

426.8 oC at 760 mmHg

Flash Point

211.9 oC

Refractive Index

1.6300 (estimate)

SMILES

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CC(=O)NC1=CC=C(C=C1)S(=O)(=O)Cl

InChI

InChI=1S/C8H8ClNO3S/c1-6(11)10-7-2-4-8(5-3-7)14(9,12)13/h2-5H,1H3,(H,10,11)

InChIKey

GRDXCFKBQWDAJH-UHFFFAOYSA-N

LogP

1.5724999999999998

Topological Polar Surface Area

63.24 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

301

Safety Information

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GHS Hazard Pictograms

H314

H335

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

InChI=1/C8H8ClNO3S/c1-6(11)10-7-2-4-8(5-3-7)14(9,12)13/h2-5H,1H3,(H,10,11
FT-0617377
4'-(Chlorosulfonyl)acetanilide
4-Acetamidobenzenesulfonyl chloride
MFCD22565760
NS00001718
4-acetylaminobenzene sulfonyl chloride
NSC-127860
4-Acetylamino-benzenesulfonyl chloride
Cloruro di N-acetilsolfanilile
NCGC00260105-01
p-(Chlorosulfonyl)acetanilide
HSDB 2712
MFCD00007442
SY350361
AC-10026
4-(ACETYLAMINO)BENZENESULFONYL CHLORIDE
4-acetamidobenzenesulphonyl chloride
N(sup 4)-Acetylsulfanilyl chloride
ACETYLAMINOBENZENE SULFONYL CHLORIDE, P-
4-acetamid obenzene-1-sulfonyl chloride
Acetanilide-p-sulfonyl chloride
EN300-19970
BP-22022
Cloruro de N-acetilsulfanililo
Tox21_202556
Q26841247
N-Acetylsulphanilyl chloride
SR-01000944744-1
4-(ACETYLAMINO)-BENZENESULFONYL CHLORIDE
121-60-8

MDL Number

MFCD00007442

Customs Code

29242995

FAQ

What is 4-Acetamidobenzenesulfonyl chloride (CAS: 121-60-8)?

4-Acetamidobenzenesulfonyl chloride is an organic compound with the chemical formula C8H9NO2SCl. It is a sulfonyl chloride derivative of acetanilide and is known for its reactivity in chemical synthesis. The compound is typically a white solid with a characteristic odor and is used as an intermediate in the production of various pharmaceutical and industrial chemicals.

What are the main uses of 4-Acetamidobenzenesulfonyl chloride (CAS: 121-60-8)?

4-Acetamidobenzenesulfonyl chloride is primarily used in the pharmaceutical industry as a building block for synthesizing drugs, including certain sulfonylureas. It also finds applications in research for developing new compounds and in industrial processes for producing intermediates in dyes and agrochemicals. Its reactivity makes it valuable in organic synthesis reactions.

Is 4-Acetamidobenzenesulfonyl chloride (CAS: 121-60-8) safe?

4-Acetamidobenzenesulfonyl chloride is considered hazardous due to its potential to cause skin and eye irritation, as well as respiratory issues. Proper handling with personal protective equipment (PPE) is essential. It should be used in well-ventilated areas and stored away from incompatible substances. Safety standards require adherence to OSHA and EPA guidelines for chemical exposure.

How should 4-Acetamidobenzenesulfonyl chloride (CAS: 121-60-8) be stored?

4-Acetamidobenzenesulfonyl chloride should be stored in a cool, dry, and well-ventilated place, away from moisture and direct light. It is best kept in a sealed container made of inert material such as glass or polyethylene. Storage conditions should maintain a temperature below 25°C and humidity levels below 60% to ensure stability and prevent degradation.